Protein Alignment Sln and MCH2

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_012701.2
• Gene: MCH2 / 853659
• SGDID: S000001704
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 647
• Identity: 108/647 - (16%)
• Similarity: 197/647 - (30%)
• Gaps: 266/647 - (41%)

  Fly   187 RAKERERDRVTVARRSKQVVKDRDSSTTTTESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKS 251
            |.::..||   |..:.....||..:..|:.     ::|.|||||||||:.......|...|....
Yeast     5 RHEDHHRD---VENKLNLNGKDDINGNTSI-----SIEVPDGGYGWFILLAFILYNFSTWGANSG 61

  Fly   252 YGVLYVEIME--TFPSSTATVASWIPAILSALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMI 314
            |.:.....:|  ||...:....:.|..:..:..|..||:.:.|...||.:.::.:|.:|....::
Yeast    62 YAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALL 126

  Fly   315 LSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIK 379
            |:.|:.:|..:.||.|||.|.|......|.:.::..:|...|:||:||..:|:..|..:..:.::
Yeast   127 LAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQ 191

  Fly   380 HLAENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTT 444
            .:.:..|....  ::..|:  :|.|.                               ||..::.|
Yeast   192 SILQKRGVKWA--LIAQCI--ICTSL-------------------------------STIALMLT 221

  Fly   445 STYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKP 509
            .|
Yeast   222 RT--------------------------------------------------------------- 223

  Fly   510 MKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSV 574
                                           :::|.|:.:..:
Yeast   224 -------------------------------THQGLRQHKRSY---------------------- 235

  Fly   575 VSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQLVESIIDGDGHLAADEDDDDDEERGPRT 639
                                                                             
Yeast   236 ----------------------------------------------------------------- 235

  Fly   640 CCERIEMYLDISLLQDPSFILMCLSVTLMSVGCPYMLYYLPAHVISIGYNKSEAGYLVAISAVLD 704
               :.|: ||..:|.:.:..|:...|:...:|...:||.|....:|:||...:..|:..:.:|..
Yeast   236 ---KFEL-LDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGS 296

  Fly   705 LIGRLGLGWLCD----------LQLFDRKKTYTLCILGAGCAVLTIPFAKTLVLVGLSAAVYGLC 759
            |:||..:|.:.|          |.|       .:.||   |..:.|| .|.|.    :|..:||.
Yeast   297 LLGRPIVGHIADKYGSLTVGMILHL-------VMAIL---CWAMWIP-CKNLA----TAIAFGLL 346

  Fly   760 LGS-----WYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVPPLAGL---MRDLSG-DY 812
            :||     |..:..: :..:.|..::..::|...:|.:..|: |.|:.||   ..|.:| ||
Yeast   347 VGSIMGTIWPTIASI-VTRIVGLQKLPGTFGSTWIFMAAFAL-VAPIIGLELRSTDTNGNDY 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	38/177 (21%)
		MFS	<656..827	CDD:119392	43/176 (24%)
		MFS_1	658..>847	CDD:284993	43/174 (25%)
MCH2	NP_012701.2	MFS_MCT_SLC16	41..428	CDD:340910	95/603 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm13433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
TreeFam	0	0.000	Not matched by this tool.
	6	5.910