Protein Alignment Sln and Slc16a3

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001033742.1
• Gene: Slc16a3 / 80879
• MGIID: 1933438
• Length: 470
• Species: Mus musculus
• Alignment Length: 657
• Identity: 134/657 - (20%)
• Similarity: 232/657 - (35%)
• Gaps: 250/657 - (38%)

  Fly   217 ESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFP---SSTATVASWIPAIL 278
            :.|...::.||||:||.::||.|.:..:.....|:..|.:.|:|..|.   |.||    ||.:||
Mouse     7 DEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTA----WISSIL 67

  Fly   279 SALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTP 343
            .|:.....||.|....||.||.|:.|||:|.::||:.:.|..|::.:.||.||:||:|..|:..|
Mouse    68 LAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQP 132

  Fly   344 GIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLY 408
            .::::::||:|.|.:|||:..:|:......|..|.:.|.::.|:.|..|||||.:|:.||.|.|.
Mouse   133 SLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALM 197

  Fly   409 RPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESK 473
            ||:.|                      |               .||.|
Mouse   198 RPLVA----------------------P---------------QVGGG----------------- 208

  Fly   474 NHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSG 538
                                                                             
Mouse   209 ----------------------------------------------------------------- 208

  Fly   539 TDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQA 603
                                                                             
Mouse   209 ----------------------------------------------------------------- 208

  Fly   604 ELGILDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLM 668
                                        .|.|||:...:|:   ||:|:.:|..|::..::.::|
Mouse   209 ----------------------------TEPRGPQRPPQRL---LDLSVFRDRGFLIYAVAASIM 242

  Fly   669 SVGCPYMLYYLPAHVIS----IGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLC 729
            .:|    |:..|..|:|    :|...::|.:|:.|...:|:..|...|::..|:   :.:.|::.
Mouse   243 VLG----LFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLK---KVRPYSVY 300

  Fly   730 ILGAGCAVLTIPFAKTLVLVGLSAAVYG----LCL--GSWYVLMPVL----LADVFGTDRISSSY 784
            :..     ..:.|.....|.|.:|..||    .|:  |..|.::..|    |..:.||.:.||:.
Mouse   301 LFS-----FAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAI 360

  Fly   785 GLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSI--LEARNHRLFVQR 847
            |||.:.:::..:..||..|.:.|.:..|:..|...|:.::..:..|::.:.  :..|......:.
Mouse   361 GLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTEP 425

  Fly   848 EEEECEE 854
            ||...||
Mouse   426 EEVASEE 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	65/178 (37%)
		MFS	<656..827	CDD:119392	41/184 (22%)
		MFS_1	658..>847	CDD:284993	43/204 (21%)
Slc16a3	NP_001033742.1	MFS_MCT3_4	21..410	CDD:340988	124/619 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850