Protein Alignment Sln and Slc16a3

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_110461.1
• Gene: Slc16a3 / 80878
• RGDID: 620603
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 133/656 - (20%)
• Similarity: 232/656 - (35%)
• Gaps: 249/656 - (37%)

  Fly   217 ESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFP---SSTATVASWIPAIL 278
            :.|...::.||||:||.::||.|.:..:.....|:..|.:.|:|..|.   |.||    ||.:||
  Rat     7 DEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTA----WISSIL 67

  Fly   279 SALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTP 343
            .|:.....||.|....||.||.|:.|||:|.::||:.:.|..|::.:.||.||:||:|..|:..|
  Rat    68 LAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQP 132

  Fly   344 GIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLY 408
            .::::::||:|.|.:|||:..:|:......|..|.:.|.::.|:.|..|||||.:|:.||.|.|.
  Rat   133 SLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALM 197

  Fly   409 RPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESK 473
            ||:.|                      |..:|             ||
  Rat   198 RPLVA----------------------PQASG-------------GA------------------ 209

  Fly   474 NHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSG 538
                                                                             
  Rat   210 ----------------------------------------------------------------- 209

  Fly   539 TDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQA 603
                                                                             
  Rat   210 ----------------------------------------------------------------- 209

  Fly   604 ELGILDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLM 668
                                         |..||:....|:   ||:|:.:|..|::..::.::|
  Rat   210 -----------------------------EPHGPQRPSPRL---LDLSVFRDRGFLIYAVAASIM 242

  Fly   669 SVGCPYMLYYLPAHVIS----IGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLC 729
            .:|    |:..|..|:|    :|...::|.:|:.|...:|:..|...|::..|:   :.:.|::.
  Rat   243 VLG----LFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLK---KVRPYSVY 300

  Fly   730 ILGAGCAVLTIPFAKTLVLVGLSAAVYG----LCL--GSWYVLMPVL----LADVFGTDRISSSY 784
            :..     ..:.|.....|.|.:|:.||    .|:  |..|.::..|    |..:.||.:.||:.
  Rat   301 LFS-----FAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAI 360

  Fly   785 GLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSIL-EARNHRLFVQRE 848
            |||.:.:::..:..||..|.:.|.:..|:..|...|:.::..:..|::.:.. ..:..|..|.:.
  Rat   361 GLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTKP 425

  Fly   849 EEECEE 854
            ||...|
  Rat   426 EEVASE 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	65/178 (37%)
		MFS	<656..827	CDD:119392	41/184 (22%)
		MFS_1	658..>847	CDD:284993	44/203 (22%)
Slc16a3	NP_110461.1	MFS_MCT3_4	21..410	CDD:340988	123/619 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339277
Domainoid	1	1.000	128	1.000	Domainoid score	I5173
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850