Protein Alignment Sln and Slc16a5

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001103038.1
• Gene: Slc16a5 / 690212
• RGDID: 1582896
• Length: 466
• Species: Rattus norvegicus
• Alignment Length: 611
• Identity: 129/611 - (21%)
• Similarity: 202/611 - (33%)
• Gaps: 218/611 - (35%)

  Fly   223 VEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVLAP 287
            :|..||.:.|.::..:...|....|.....||.:.::...|.:|.:. .||.|:|:.|:.....|
  Rat     5 LEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSE-TSWFPSIMGAMLHCGGP 68

  Fly   288 LSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYF 352
            |.|.|.:||.||..:.:||:..::||:.|.|:.||:||.||.|::||:|...|....|.:|..||
  Rat    69 LCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYF 133

  Fly   353 DKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQ 417
            .:.|.|||.:...|.:.|..:.|:|.::|.|..|:.|..||.||..||.||...:.||::.
  Rat   134 VRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVAT---- 194

  Fly   418 DSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYASK 482
                         |.|..|.
  Rat   195 -------------NVDPEPK--------------------------------------------- 201

  Fly   483 QPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRR 547
                                                    |||
  Rat   202 ----------------------------------------EDL---------------------- 204

  Fly   548 RRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQL 612
                                 |.||...:|..
  Rat   205 ---------------------LLPPKTPTRSC--------------------------------- 215

  Fly   613 VESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQ-DPSFILMCLSVTLMSVGCPYML 676
                      ||              ||...|:.||...:|: :..|.:.....|.|::|.....
  Rat   216 ----------LA--------------TCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPH 256

  Fly   677 YYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLC---DLQLFDRKKTYTLCILGAG---- 734
            .:|..:.:..|..:..|..|::|....::..|...|.|.   .|..: ||..:.:.||..|
  Rat   257 IFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAY-RKYLFAVAILINGLTNL 320

  Fly   735 -CAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISV 798
             |.|    .|...||:|. ..||.|.:....:|:..:|.|:...||..|:.||..:...:|::..
  Rat   321 ICTV----SADFRVLLGY-CLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLIS 380

  Fly   799 PPLAGLMRDLSGDYEICFYCMGSCMV 824
            ||||||:.|.:.::...||.....::
  Rat   381 PPLAGLLLDTTNNFNYVFYMSSGLLI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	61/175 (35%)
		MFS	<656..827	CDD:119392	45/177 (25%)
		MFS_1	658..>847	CDD:284993	45/175 (26%)
Slc16a5	NP_001103038.1	2A0113	1..432	CDD:273325	129/611 (21%)
		MFS	32..412	CDD:119392	123/584 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339232
Domainoid	1	1.000	128	1.000	Domainoid score	I5173
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850