DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sln and Slc16a9

DIOPT Version :9

Sequence 1:NP_610706.1 Gene:Sln / 36263 FlyBaseID:FBgn0033657 Length:855 Species:Drosophila melanogaster
Sequence 2:NP_080083.2 Gene:Slc16a9 / 66859 MGIID:1914109 Length:508 Species:Mus musculus


Alignment Length:619 Identity:139/619 - (22%)
Similarity:236/619 - (38%) Gaps:171/619 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   226 PDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVLAPLSS 290
            ||||:||.||..:|..||...|...:.||||||.::.|.......| |:.::.|.:.|:.:|:.|
Mouse     7 PDGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKGKTA-WVGSLASGVGLLASPVCS 70

  Fly   291 ALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDKH 355
            .....|..|.|....|...|.|::||..|.::..|..::|::.|:|.||..|..:.|..||||..
Mouse    71 LFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSR 135

  Fly   356 RALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQDSG 420
            |.||.|:..:|::.|.||...|.:.|.|..|..|.:||:|...|::....:|.||:     |.|.
Mouse   136 RGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPL-----QTSD 195

  Fly   421 QGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKN---HLNYYASK 482
            ....|...|.|                           :.|::  .::.|:.||   .:|:....
Mouse   196 CPFPEKTAPEN---------------------------VPDRY--SMYNEKEKNPEETMNFQDKG 231

  Fly   483 QPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRR 547
            ..::||.....|                                    |      |.:::     
Mouse   232 YSSEDKCLPNGD------------------------------------W------GRETS----- 249

  Fly   548 RRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQL 612
                                           |.||:.|..........|::.|||...       
Mouse   250 -------------------------------LPKSLAIAAHTKEPETYKKKVVEQTNF------- 276

  Fly   613 VESIIDGDGHLAADEDDDDDEERGPRTCCERI-----EMYLD-----ISLLQDPSFILMCLSVTL 667
                                        |:::     ::|.:     .||.::..|..:.:::.|
Mouse   277 ----------------------------CKQLAKRKWQLYRNYCGETASLFKNKVFSALFIAILL 313

  Fly   668 MSVG--CPYMLYYLPAHVISIGYNKSEAGY---LVAISAVLDLIGRLGLGWLCDLQLFDRKKTYT 727
            ..:|  .|.:|    ...::..|:..|...   |::|..::..:|:|.||.|.|.:..:....|.
Mouse   314 FDIGGFPPSLL----MEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLGILADFKWINTLYLYV 374

  Fly   728 LCILGAGCAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQS 792
            ..::..|.|:..|||||:.|.:.:.:.:.|...|:|.: .|.:.....|.|:::.:||::..|..
Mouse   375 ATLIITGLALCAIPFAKSYVTLAILSGILGFLTGNWSI-FPYVTTKTVGIDKLAHAYGILMFFAG 438

  Fly   793 IGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLG 826
            :|....||:.|...|.:..|:|.||..|.|::||
Mouse   439 LGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 472

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SlnNP_610706.1 MFS 235..>411 CDD:119392 58/175 (33%)
MFS <656..827 CDD:119392 46/176 (26%)
MFS_1 658..>847 CDD:284993 46/174 (26%)
Slc16a9NP_080083.2 MFS_MCT9 12..479 CDD:340986 135/614 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835611
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2504
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D916876at2759
OrthoFinder 1 1.000 - - FOG0000033
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.750

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