Protein Alignment Sln and slc16a6b

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001352167.1
• Gene: slc16a6b / 561766
• ZFINID: ZDB-GENE-110208-3
• Length: 527
• Species: Danio rerio
• Alignment Length: 651
• Identity: 155/651 - (23%)
• Similarity: 243/651 - (37%)
• Gaps: 184/651 - (28%)

  Fly   221 PNV--EPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCL 283
            |||  |.||||:||.:....|.|:.:..|::|::|:...::|..|..:.:.| ||..:|...:..
Zfish    10 PNVYSEVPDGGWGWMVAAAFFFVEVFTYGIIKTFGIFLQDLMTEFHETNSRV-SWAVSICVFVMA 73

  Fly   284 VLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIV 348
            ..||||:.|..||..|.||.|||...::|.|.:....|:..:.:|.|::.|:|..|:..|.:.|:
Zfish    74 FTAPLSTLLSNRFGHRPVVMVGGFLISLGTITTALTQSIDEMYITMGIVAGLGYCLTFLPTVTIL 138

  Fly   349 SQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISA 413
            ||||.|.|:|...|..:|...........:..|.|..|:...::::|.....:.|...|.:||
Zfish   139 SQYFSKRRSLVTSIASTGECFSMLAFAPAMNALKEQIGWRYCLMVIGVLQASIIVCGALLKPI-- 201

  Fly   414 YTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNY 478
                        ..||     .|:|.                              |.|.:.|..
Zfish   202 ------------VIKP-----KPATQ------------------------------EASTSPLKV 219

  Fly   479 YASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNR 543
            ..||..|:::....|.|.|                                      .||..|
Zfish   220 LDSKYDAENEFTCTSFDSV--------------------------------------DSGVQS-- 244

  Fly   544 GSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGIL 608
                          ||..|.:|.|...         .|..|..:|        :.|::|
Zfish   245 --------------ISSSQVNLAKEQQ---------KKEEEGESP--------ETPLKQ------ 272

  Fly   609 DSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLMSVGCP 673
                              :.:|....|         ...||.|:|:|.||....|.....::|..
Zfish   273 ------------------KQEDSSVSR---------TKLLDFSVLRDASFNCYALFGLFATLGFF 310

  Fly   674 YMLYYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRK---KTYTLCILGAGC 735
            ....|:....:|.|.::..|.|:::..||.::.|||.:||     :.:||   |.|.|.|    |
Zfish   311 APQIYIIQLSVSRGVSQKSATYMLSAMAVAEIGGRLSMGW-----VLNRKPIRKIYILLI----C 366

  Fly   736 AVLTIPFAKTLVLV----GL--SAAVYGLCLG---SWYVLMPVLLA-DVFGTDRISSSYGLVRMF 790
            .||..|.......|    ||  .:.:||..||   |.::  |:|.. ||.|..|:||:.|:....
Zfish   367 TVLLCPVLVVFTFVSEFWGLMSCSCLYGFLLGTVASSHI--PMLAEDDVIGIQRMSSAVGVYVCI 429

  Fly   791 QSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMV-LGTTPLIVWSILEARNHRLFVQREEEECEE 854
            ||...::.|||.|.:.|.:.:|...||   ||.. :|...|.:..:..|:....|.:|:.::.:.
Zfish   430 QSFAGLAGPPLGGFLVDQTNNYGSAFY---SCAAGMGVGALFLGLVRPAKTGLCFGKRKRKDQQS 491

  Fly   855 A 855
            |
Zfish   492 A 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	49/175 (28%)
		MFS	<656..827	CDD:119392	55/184 (30%)
		MFS_1	658..>847	CDD:284993	58/202 (29%)
slc16a6b	NP_001352167.1	2A0111	17..512	CDD:331689	151/644 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578924
Domainoid	1	1.000	128	1.000	Domainoid score	I5252
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850