Protein Alignment Sln and slc16a12b

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001139286.1
• Gene: slc16a12b / 449947
• ZFINID: ZDB-GENE-050522-80
• Length: 488
• Species: Danio rerio
• Alignment Length: 652
• Identity: 159/652 - (24%)
• Similarity: 252/652 - (38%)
• Gaps: 206/652 - (31%)

  Fly   204 QVVKDRDSSTTTTESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTA 268
            :||...|......:.||  |.|||||:||.||.|.|.|......:.:...:.:||....|....:
Zfish     4 KVVGRTDYMAQEKKKGG--VLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYS 66

  Fly   269 TVASWIPAILSALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLT 333
            ..| ||.:::....::.|||.|.:..:.|||..|.:||...::|::||.|||||.:|..|.|:||
Zfish    67 GTA-WIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLT 130

  Fly   334 GIGGGLSTTPGIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCM 398
            |:|..|..||.|.:|..||.:.:|||.||.:||:..|:|||..:::.|.|:..:.|.:|||||.:
Zfish   131 GLGFALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFV 195

  Fly   399 LHVCVSATLYRPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKF 463
            |::||...|.|||..         :||.|.||..|   |..|
Zfish   196 LNLCVCGALLRPIIL---------KEEEACPLPVD---SECG----------------------- 225

  Fly   464 IEHLFLEESKNHLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTD 528
                           |:.|.|.
Zfish   226 ---------------YSVKPPT------------------------------------------- 232

  Fly   529 STWVYRKHSGTDSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLS 593
                        .|.|..|                                          |..|
Zfish   233 ------------LNGGPTR------------------------------------------SAAS 243

  Fly   594 DLKQQPVEQAELGILDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSF 658
            |.||:                                         |.:.::.|   ..|..|.|
Zfish   244 DAKQR-----------------------------------------CFQSMQEY---HFLLMPDF 264

  Fly   659 ILMCLSVTLMSVGCPYMLYYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRK 723
            :::..|..|::.||.....||..:.:.:|.....|.:|::|..|:|::|.:..|||.|.:..  |
Zfish   265 LVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCL--K 327

  Fly   724 KTYTLCILGA----GCAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSY 784
            |...:|.:.|    |...|.||..:|.|.:...:.:||...|::..|:||:.:||.|...:||:.
Zfish   328 KYRNICYMFAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSAL 392

  Fly   785 GLVRMFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSILEARNHRLFVQREE 849
            |:|....::..:..||:.|.:.|.:|.|...|:..|..::  ::.|:::|:...|    :.||.:
Zfish   393 GVVYFLHAVPYLVSPPIGGWLVDTTGTYTATFFLSGFALI--SSSLLLFSVAIIR----YCQRNQ 451

  Fly   850 EE 851
            ::
Zfish   452 KK 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	66/175 (38%)
		MFS	<656..827	CDD:119392	50/174 (29%)
		MFS_1	658..>847	CDD:284993	52/192 (27%)
slc16a12b	NP_001139286.1	MFS	33..430	CDD:119392	140/590 (24%)
		MFS_1	37..407	CDD:284993	130/563 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578928
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.850