Protein Alignment Sln and slc16a12

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_989310.1
• Gene: slc16a12 / 394932
• XenbaseID: XB-GENE-1012784
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 627
• Identity: 152/627 - (24%)
• Similarity: 240/627 - (38%)
• Gaps: 198/627 - (31%)

  Fly   215 TTESGGPNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILS 279
            |.|....:..|||||:||.||.|.|.|......:.:...:.:||....|....|..| ||.:|:.
 Frog     2 TQEKRNLHKAPPDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFAQDYARTA-WIHSIVD 65

  Fly   280 ALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPG 344
            ...::.||:.|.:...|||:..:.:||:..:.|::||.|||||.:|.||.|||||:|..|..:|.
 Frog    66 CSTMLCAPIGSYVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLGVLTGLGFALCYSPA 130

  Fly   345 IVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYR 409
            |.:|.:||:|.:|||.||.:||:..|:|||..:::.|.|...:.|.:|||||.:.::||...|.|
 Frog   131 IAMVGKYFEKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCGALMR 195

  Fly   410 PISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKN 474
            ||:                 |.||
 Frog   196 PIT-----------------LKED----------------------------------------- 202

  Fly   475 HLNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGT 539
            .|:|                              |:|:
 Frog   203 SLHY------------------------------PLKQ--------------------------- 210

  Fly   540 DSNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAE 604
                                                                    :|...|..:
 Frog   211 --------------------------------------------------------EQMENEPTQ 219

  Fly   605 LGILDSQLVESIIDGDGHLAADEDDDDDEERGPRTC-CERIEMYLDISLLQDPSFILMCLSVTLM 668
            .|.|||. ...:.....|              .|.| |.:.|    .|.|..|.|:::.:|...:
 Frog   220 SGRLDSS-CSPLCQDCSH--------------KRLCYCTKKE----YSFLLKPKFMVLAVSFLFL 265

  Fly   669 SVGCPYMLYYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLCILGA 733
            :.||.....||..:.:::|.:..||.:|::|..::|::|.:..||:.|.: |.:|..| .|.|.|
 Frog   266 AYGCSPPFVYLVPYALNVGVSNQEAAFLMSILGIIDIVGNITFGWVTDTR-FLKKHRY-CCYLIA 328

  Fly   734 ----GCAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIG 794
                |...|.:|......|:...:.::|...|::..|:||:..||.||..:||:.|:|....::.
 Frog   329 VGLDGLCCLFLPILTRFQLLVPFSVMFGYFDGAYVALIPVVTGDVVGTSSLSSALGVVFFLHAVP 393

  Fly   795 AISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSIL 836
            .:..||:||.:.|.:|||...|...|..|:.....|.:..|:
 Frog   394 YLVSPPIAGWLVDTTGDYTAAFLLSGFSMIFCAVLLALAKII 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	67/175 (38%)
		MFS	<656..827	CDD:119392	51/174 (29%)
		MFS_1	658..>847	CDD:284993	52/183 (28%)
slc16a12	NP_989310.1	2A0111	12..444	CDD:331689	150/617 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		otm48502
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020