Protein Alignment Sln and slc16a1b

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_956379.1
• Gene: slc16a1b / 368274
• ZFINID: ZDB-GENE-030515-5
• Length: 461
• Species: Danio rerio
• Alignment Length: 649
• Identity: 143/649 - (22%)
• Similarity: 228/649 - (35%)
• Gaps: 232/649 - (35%)

  Fly   218 SGGP-NVEPPDGGYGWFIVFGAF-SVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSA 280
            :||| ...||:||:||.:|.||| |:.|..| ..||..|.:.|| |...::|::..|||.:|:.|
Zfish     5 TGGPVGYTPPEGGWGWAVVVGAFISIGFSYA-FPKSITVFFKEI-EVIFNATSSQVSWISSIMLA 67

  Fly   281 LCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGI 345
            :.....|:||.|..:|..|.::..||.....|::.:.|..::..|....||:.|:|...:..|.:
Zfish    68 VMYAGGPISSILVNKFGSRPIMIAGGCLSGTGLVAASFCDTVEGLYFCVGVIGGLGLAFNLNPAL 132

  Fly   346 VIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRP 410
            .::.:||.|.|.:||||.::|:......|..|...|.:..|:.|:.|||||.:|:.||:.:|.||
Zfish   133 TMIGKYFYKRRPIANGIAMAGSPVFLSTLAPLNSWLFDQFGWRGSFLILGGALLNCCVAGSLMRP 197

  Fly   411 ISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNH 475
            |.              .||
Zfish   198 IG--------------PKP---------------------------------------------- 202

  Fly   476 LNYYASKQPAQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTD 540
                   |||..|...|              |||.:|
Zfish   203 -------QPAIPKEDAE--------------IKPQEK---------------------------- 218

  Fly   541 SNRGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAEL 605
                                                                             
Zfish   219 ----------------------------------------------------------------- 218

  Fly   606 GILDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLMSV 670
                                            :|..:.|..:||::|.....|:|..|...:|..
Zfish   219 --------------------------------KTVMQTINGFLDLTLFTHRGFLLYLLGNVIMFF 251

  Fly   671 GCPYMLYYLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCD-------LQLFDRKKTYTL 728
            |....|.:|..:..|...:|.:|.:|::|.|..|:|.|..:|.:.:       :|.|     :..
Zfish   252 GLFAPLVFLSNYAKSKHISKDKAAFLLSILAFTDMIARPSMGLVANTRWVRPRIQYF-----FAA 311

  Fly   729 CILGAGCAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVL---LADVFGTDRISSSYGLVRMF 790
            .:|..|...|..|.:...:...:.|..:|:..| |  |..||   |.|:.|..|.||:.|||.:.
Zfish   312 SVLYNGVCHLLAPLSTDYLGFAIYAVFFGVAFG-W--LSSVLFETLMDLVGAQRFSSAVGLVTIV 373

  Fly   791 QSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIVWSILEARNHRLFVQREEEECEE 854
            :....:..|||.|.:.|:..||:..:...|..:|:.:..|.|...:   |:|| |.:|::|.|:
Zfish   374 ECAPVLLGPPLLGRLNDIYDDYKYTYQGCGIVLVIASIFLFVGMGI---NYRL-VDKEKKEEEK 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	59/176 (34%)
		MFS	<656..827	CDD:119392	48/180 (27%)
		MFS_1	658..>847	CDD:284993	54/198 (27%)
slc16a1b	NP_956379.1	2A0113	1..442	CDD:273325	143/649 (22%)
		MFS	20..415	CDD:119392	127/610 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578880
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518644at33208
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750