Protein Alignment Sln and hrm

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001286141.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 205/688 - (29%)
• Similarity: 323/688 - (46%)
• Gaps: 91/688 - (13%)

  Fly   202 SKQVVKDRDSSTTTTESGGPNVE-------------PPDGGYGWFIVFGAFSVQFWVAGLVKSYG 253
            ||...||...:..|.||....|.             |||||:||.::.|:......:.|.:||:|
  Fly    13 SKINQKDHKPNGNTNESRHKTVSLINKKDDKEYDLVPPDGGWGWLVLLGSCLTNILIPGTIKSFG 77

  Fly   254 VLYVEIMETFPSSTATVASWIPAILSALCLVLAPLSSALCQRFSCRTVVFVGGIFCAMGMILSYF 318
            ||:.|..:.| :|:.|.|:||||:...|...|.|:||.|..::|.|||..:||...::|||||::
  Fly    78 VLFSEFTDAF-NSSPTKAAWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFW 141

  Fly   319 ATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDKHRALANGICVSGTAAGSFILPVLIKHLAE 383
            |:|:..|.:::|||.|||.|||..|.:.||:.||.|.|.||||:|:||:|.||.|||.|::.|.|
  Fly   142 ASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLE 206

  Fly   384 NCGFHGTILILGGCMLHVCVSATLYRPISAYTDQDSGQGQEETAKPLNEDINPSTTGILTTSTYL 448
            ..|:||:.||:||..|:|.|:|..|.|:..:..:.....|.....|..|||     ||:.....:
  Fly   207 TYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRARQALENIPEEEDI-----GIVMKFENV 266

  Fly   449 DTCDVGAGHELSDKFI-------EHLFLEESKNHLNYYASKQPAQDKSAQESDDEVKD---IIGE 503
            |  :....:|.:||.:       ..|:| .....|.:..|...|..:|..:|.||.:.   .|..
  Fly   267 D--EPVPKNEPADKPLLPYNSPPSPLYL-PGDERLQFVRSASAAVVQSYSKSGDEFQSRSRKIST 328

  Fly   504 TTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSN-----RGSRRRRNVFANDEVISKIQA 563
            ...:....:..:.|.|:|...|       |....|..|:     |.|.:.|        :||
  Fly   329 PVRLPQRNQTFTPGQLNSQSSL-------YAVPEGRSSSNKLTLRNSSKSR--------LSK--- 375

  Fly   564 HLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVE---QAELGILDSQLVESIIDGDGHLAA 625
                  ..||.     |..:.:.||... |.|..||.|   ...|..:.|       .|.||...
  Fly   376 ------RSPST-----SSFLYVSTPYHG-STLSFQPKEFSSHLSLRSMGS-------SGTGHAGD 421

  Fly   626 DEDDD----DDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLMSVGCPYMLYYLPAHVISI 686
            ....|    |.:.||.....:| ..:.|:|||:||.::::.:|.:..::.....:..||:...:.
  Fly   422 STGQDGSYADVDARGQAQQPQR-SKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEAR 485

  Fly   687 GYNKSEAGYLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLCILGAGCAVLTIPFAKTLVLVGL 751
            |:|||.:.||:::.:..|||||:|...|.|:....:...:...:..:|.::..:|||.|...|..
  Fly   486 GFNKSLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCF 550

  Fly   752 SAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVPPLAGLMRDLSGDYEICF 816
            ..|::||..|.:..:..|::||:.||:|::||||:......:..:..|||.....:...||...|
  Fly   551 WCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDYNPLF 615

  Fly   817 YCMGSCMVLGTTPLIVWSILEARNHRLFVQREEEECEE 854
            :.:|..::.|.:   :||.:.      ::.|.:...||
  Fly   616 HALGLTLLAGAS---LWSFMP------WINRRKANAEE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	80/175 (46%)
		MFS	<656..827	CDD:119392	45/170 (26%)
		MFS_1	658..>847	CDD:284993	47/188 (25%)
hrm	NP_001286141.1	2A0113	49..653	CDD:273325	197/652 (30%)
		MFS	59..>234	CDD:119392	80/175 (46%)
		MFS	<449..633	CDD:119392	52/186 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I4618
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	117	1.000	Inparanoid score	I274
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122935at6656
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm13433
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
	9	8.970