Protein Alignment Sln and SLC16A11

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001357478.1
• Gene: SLC16A11 / 162515
• HGNCID: 23093
• Length: 447
• Species: Homo sapiens
• Alignment Length: 624
• Identity: 137/624 - (21%)
• Similarity: 209/624 - (33%)
• Gaps: 256/624 - (41%)

  Fly   225 PPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVLAPLS 289
            |||||:||.:...||::.....||::|.|:.:.::.|.|..|....| ||.|:..|:....:|:.
Human     8 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTA-WISALALAVQQAASPVG 71

  Fly   290 SALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQYFDK 354
            |||..|:..|.||.|||:..::|.:.|.||:.||||.|..|:|.|.|..|...|.:..:|:||.:
Human    72 SALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSR 136

  Fly   355 HRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISAYTDQDS 419
            .|.||.|:.::|..|.|.:|...::.|.:..|:.|.:|:||...||:.....|..|:
Human   137 RRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPL-------- 193

  Fly   420 GQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYASKQP 484
                                                                             
Human   194 ----------------------------------------------------------------- 193

  Fly   485 AQDKSAQESDDEVKDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSNRGSRRRR 549
                                                                             
Human   194 ----------------------------------------------------------------- 193

  Fly   550 NVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGILDSQLVE 614
             |...|            |.:||                        :.|
Human   194 -VLPGD------------PPAPP------------------------RSP--------------- 206

  Fly   615 SIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLMSVG--CPYMLY 677
                    |||                      |.:||....:|.:..|...|:..|  .||:
Human   207 --------LAA----------------------LGLSLFTRRAFSIFALGTALVGGGYFVPYV-- 239

  Fly   678 YLPAHVISIGYNKSEAGYLVAISAVLDLIGRLGLGWLCD---------LQLFDRKKTYTLCILGA 733
            :|..|.:..|.....|..:||::|:.|...||..|||.|         |.:|.       .:.|.
Human   240 HLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFG-------ALTGL 297

  Fly   734 GCAVLTIPFAKTLVLVG---------LSAAV-YGLCLGSWYVLMPVLLADVFGTDRISSSYGLVR 788
            |..|:.:     :.:||         |:||| |||..||:..|:..:|..:.|...:..:.|||.
Human   298 GLWVVGL-----VPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVM 357

  Fly   789 MFQSIGAISVPPLAGLMRDLSGDYEICFYCMGSCMVLGT 827
            |..|:|.:..|||:|.:||.:||:...|...||.::.|:
Human   358 MLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGS 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	60/175 (34%)
		MFS	<656..827	CDD:119392	56/191 (29%)
		MFS_1	658..>847	CDD:284993	57/191 (30%)
SLC16A11	NP_001357478.1	MFS	14..403	CDD:355786	132/618 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145561
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850