Protein Alignment Sln and SLC16A14

DIOPT Version :9

• Sequence 1: NP_610706.1
• Gene: Sln / 36263
• FlyBaseID: FBgn0033657
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 139/618 - (22%)
• Similarity: 246/618 - (39%)
• Gaps: 159/618 - (25%)

  Fly   221 PNVEPPDGGYGWFIVFGAFSVQFWVAGLVKSYGVLYVEIMETFPSSTATVASWIPAILSALCLVL 285
            ||:   |||:.|.:|..:|.|...:.|...:.|||.||.:|.|..|....| |:.::...:.|::
Human    26 PNI---DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTA-WVSSLSMGITLIV 86

  Fly   286 APLSSALCQRFSCRTVVFVGGIFCAMGMILSYFATSLLHLLLTFGVLTGIGGGLSTTPGIVIVSQ 350
            .|..........||....:||:..::|.:||.:|.::.:|.:||||..|:|.|::..|.:|:|.:
Human    87 GPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGR 151

  Fly   351 YFDKHRALANGICVSGTAAGSFILPVLIKHLAENCGFHGTILILGGCMLHVCVSATLYRPISAYT 415
            ||.|.||||.|:..:||..|:|::.||:|:|....|:...:||.|...|::||...|.||:|...
Human   152 YFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGK 216

  Fly   416 DQDSGQGQEETAKPLNEDINPSTTGILTTSTYLDTCDVGAGHELSDKFIEHLFLEESKNHLNYYA 480
            :.:....::....|.:...:..:||   .....:..|.|.|:|
Human   217 NPNDPGEKDVRGLPAHSTESVKSTG---QQGRTEEKDGGLGNE---------------------- 256

  Fly   481 SKQPAQDKSAQESDDEV---KDIIGETTFIKPMKKVRSSGLLHSVEDLSTDSTWVYRKHSGTDSN 542
              :...|..|||..|:.   |::..    ::.:|.|  |.|...|.....|  | |..:.||.|
Human   257 --ETLCDLQAQECPDQAGHRKNMCA----LRILKTV--SWLTMRVRKGFED--W-YSGYFGTAS- 309

  Fly   543 RGSRRRRNVFANDEVISKIQAHLEKPLSPPSVVSRGLSKSMEIPTPVSNLSDLKQQPVEQAELGI 607
                    :|.|...::
Human   310 --------LFTNRMFVA------------------------------------------------ 318

  Fly   608 LDSQLVESIIDGDGHLAADEDDDDDEERGPRTCCERIEMYLDISLLQDPSFILMCLSVTLMSVGC 672
                                                   ::..:|....||::
Human   319 ---------------------------------------FIFWALFAYSSFVI------------ 332

  Fly   673 PYMLYYLPAHVISIGYNKSEAG---YLVAISAVLDLIGRLGLGWLCDLQLFDRKKTYTLCILGAG 734
            |::  :|| .:::: ||.||..   .|.:|.|::.:.|::.||.:.||........:.|......
Human   333 PFI--HLP-EIVNL-YNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLV 393

  Fly   735 CAVLTIPFAKTLVLVGLSAAVYGLCLGSWYVLMPVLLADVFGTDRISSSYGLVRMFQSIGAISVP 799
            .::..:|...|...:.:..|:.|...| ::.||||:..|:.|.:.::::||::.....|.|:..|
Human   394 LSIFILPLMHTYAGLAVICALIGFSSG-YFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGP 457

  Fly   800 PLAGLMRDLSGDYEICFYCMGSCMVLGTTPLIV 832
            |.||.:.|::..|:..||..|...::|...|::
Human   458 PFAGWIYDITQKYDFSFYICGLLYMIGILFLLI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sln	NP_610706.1	MFS	235..>411	CDD:119392	60/175 (34%)
		MFS	<656..827	CDD:119392	42/173 (24%)
		MFS_1	658..>847	CDD:284993	43/178 (24%)
SLC16A14	NP_689740.2	2A0111	24..490	CDD:331689	139/616 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		5/43 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750