DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S2P and AT4G20310

DIOPT Version :9

Sequence 1:	NP_610705.1	Gene:	S2P / 36262	FlyBaseID:	FBgn0033656	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001328927.1	Gene:	AT4G20310 / 827778	AraportID:	AT4G20310	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	119/507 - (23%)
Similarity:	205/507 - (40%)	Gaps:	89/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SAFNRTLLRWGSAGNSCTRR---VMITSFNVGV-LVTFSLLPIGLILLIATIFSSGEQDSSSSVS 113
            |.||..:.|.|       ||   |:...|::|: ....||:.:.:.||:.  |.|....|:...|
plant    40 SNFNEPIFRLG-------RRFSGVLKVWFSIGLGFGVASLILVTVFLLLQ--FHSNPLFSNRLTS 95

  Fly   114 SPVGVPVQLEILLPGVNLPLEEIGYYITTLVLCLVVHEMGHALAAVMEDVPVTGFGIKFIFCLPL 178
            :..|       ..|...:.|..|.|.:.:.|:.:.|||:||||||..|.:.:....:......|.
plant    96 AVFG-------FSPSTRVSLSGIAYVLVSTVITVSVHELGHALAAASEGIQMEYIAVFIAAIFPG 153

  Fly   179 AYTELSHDHLNSLRWFRKLRVLCAGIWHNFVFAGVCYLLISTVGITMSPLYAYNQHVVVTELTRK 243
            ......:|.|.||..|..||:.|||||||.||..:|...:..:.:.:||.|.:.:.:.|.::...
plant   154 GLVAFDNDVLQSLPSFNALRIYCAGIWHNAVFCALCVFALFLLPVMLSPFYKHGESLTVVDVPSV 218

  Fly   244 SPLRGERGLQVDNQITQVNGCPVNSEESWVTCL-----------QNSLKL--------KPGYCVS 289
            |||.|.  |...:.|..::|..|:....|:...           ..||.|        ..||||.
plant   219 SPLFGY--LSPGDVIVSLDGIQVHKPSEWLELAAILDKENSKTSNGSLYLGGSRRFHHGKGYCVP 281

  Fly   290 ADFVQLNDESSAISHHSIDGQLQCCDELNPNVSCFEVVEDANGDVPVELPQHVCLNVRRTLEEVS 354
            ...::     .......::.|..|..:|    :.|..:..:|..:   ....|||:.:..::  .
plant   282 ISLIE-----EGYKGKMVENQFVCPGDL----TAFRTMPCSNAAI---REVSVCLDAKDIVK--L 332

  Fly   355 EHCSSG-------------VCNEG-FCLRPLIRN--ITAIMTFKRQNFR-----------GEKLP 392
            :.|..|             ||.:| .||:.:...  :...:|:||.:.:           ...|.
plant   333 QKCGDGWVTTSDTDNQSDCVCPQGDLCLQAMQSPGVLWTEITYKRTSSQDCSRLGLDFNTSNCLG 397

  Fly   393 PVIYVGHPWDVTRTVEVSAFVPR--YSLLKAAWPDAWLLLLKYNVVFSIGLALINAIPCFGFDGA 455
            ..::||....::.:|.::|:.||  ::....::|:.....|......|:.|.|:|::|.:..||.
plant   398 TFVFVGDLIAMSHSVHLTAYQPRWLFNFFGKSFPNILERSLTCTFHVSLALVLLNSLPVYYLDGE 462

  Fly   456 HITSTVIHSFLVGRVDQHAKRDIISLIITSVGSLLFALALLKVAWLSFLRPL 507
            .|..:.:.||.  .:....|:..:.:.:.. ||||..||..::..|..  ||
plant   463 SILESSLQSFT--WLSPRKKKKALQVCLVG-GSLLSFLAFFRIFLLGL--PL 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S2P	NP_610705.1	S2P-M50	6..>218	CDD:299148	52/168 (31%)
		RseP	136..508	CDD:223821	98/420 (23%)
		S2P-M50	<427..494	CDD:299148	16/66 (24%)
AT4G20310	NP_001328927.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2606
eggNOG	1	0.900	-	-		E1_COG0750
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9287
Inparanoid	1	1.050	103	1.000	Inparanoid score	I2153
OMA	1	1.010	-	-		QHG55798
OrthoDB	1	1.010	-	-		D1012405at2759
OrthoFinder	1	1.000	-	-		FOG0006242
OrthoInspector	1	1.000	-	-		oto3845
orthoMCL	1	0.900	-	-		OOG6_103384
Panther	1	1.100	-	-	LDO	PTHR13325
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4524
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840