Protein Alignment S2P and Mbtps2

DIOPT Version :9

• Sequence 1: NP_610705.1
• Gene: S2P / 36262
• FlyBaseID: FBgn0033656
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001030179.1
• Gene: Mbtps2 / 302705
• RGDID: 1566171
• Length: 519
• Species: Rattus norvegicus
• Alignment Length: 537
• Identity: 160/537 - (29%)
• Similarity: 264/537 - (49%)
• Gaps: 58/537 - (10%)

  Fly     1 MDPFVFFIVLASLYGVLYFFDRFFKSCMHY--PYDAFLKNTGLSINFMSLHWHTSAFNRTLLRWG 63
            |.|....:|:...:..:|..|...||.:::  .|:.:|:|.||||:...:.|.||.|||....||
  Rat     1 MIPVSLVVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWG 65

  Fly    64 SAGNSCTRRVMITSFNVGVLV-------TFSLLPIGLILLIATIF----------------SSGE 105
            ..    ..|::...||.|::.       :|.||...|:..:|.:.                ||..
  Rat    66 RR----KARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSS 126

  Fly   106 QDSSSSVSSPVGVPVQLEILLPGVNLPLEEIGYYITTLVLCLVVHEMGHALAAVMEDVPVTGFGI 170
            ..||||.||.:.....|::::||:|||:.::.|:...:::..||||:||.:||:.|.|...||||
  Rat   127 SSSSSSSSSSLHNDQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGI 191

  Fly   171 KFIFCLPLAYTELSHDHLNSLRWFRKLRVLCAGIWHNFVFAGVCYLLISTVGITMSPLYAYNQHV 235
            ......|.|:.:|...||..:...::||:.|||||||||.|.:..|.:..:.:.:.|.|.....|
  Rat   192 FLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGV 256

  Fly   236 VVTELTRKSPLRGERGLQVDNQITQVNGCPVNSEESWVTCLQNSLKLKP--GYCVSADFVQLNDE 298
            ::||:...||..|.|||.|.:.:|.:..|||.:.:.|..|| :::..:|  |||:||..:|  ..
  Rat   257 LITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECL-DTIAYEPQIGYCISASTLQ--QL 318

  Fly   299 SSAI-SHHSIDGQLQCCDELNPNVSCFEVVEDANGDVPVELPQHVCLNVRRTLEEV-----SEHC 357
            |..: ::..:||..:||:..:....||....:.|..:      |.||..|:.:|..     ::.|
  Rat   319 SFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRL------HTCLPARKAVEATQVCRSNKDC 377

  Fly   358 SSGVCNEGFCLRPLIRNITAIMTFKRQNFRGEKLPP---VIYVGHPWDVTRTVEVSAFVPRYSLL 419
            .|. .:..||:.|.:...|.::..|.        ||   ::|||||..:..||.:::|:||::.|
  Rat   378 KSS-SSSSFCIVPSLETHTRLIKVKH--------PPQIDMLYVGHPLHLHYTVSITSFIPRFNFL 433

  Fly   420 KAAWPDAWLLLLKYNVVFSIGLALINAIPCFGFDGAHITSTVIHSFLVGRVDQHAKRDIISLIIT 484
            ....|......:||.:..|..||::||:|||..||..|.::.:.:.|...:..:..:|:|...|.
  Rat   434 SIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFIL 498

  Fly   485 SVGSLLFALALLKVAWL 501
            ..||:|.|..:....|:
  Rat   499 LGGSVLLAANVTLGLWM 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S2P	NP_610705.1	S2P-M50	6..>218	CDD:299148	76/236 (32%)
		RseP	136..508	CDD:223821	115/377 (31%)
		S2P-M50	<427..494	CDD:299148	21/66 (32%)
Mbtps2	NP_001030179.1	S2P-M50_PDZ_SREBP	14..>229	CDD:100083	70/218 (32%)
		PDZ	<255..>299	CDD:294084	17/44 (39%)
		S2P-M50	<419..508	CDD:100078	28/88 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334434
Domainoid	1	1.000	181	1.000	Domainoid score	I3406
eggNOG	1	0.900	-	-		E1_COG0750
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9287
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3186
OMA	1	1.010	-	-		QHG55798
OrthoDB	1	1.010	-	-		D1012405at2759
OrthoFinder	1	1.000	-	-		FOG0006242
OrthoInspector	1	1.000	-	-		oto96156
orthoMCL	1	0.900	-	-		OOG6_103384
Panther	1	1.100	-	-	LDO	PTHR13325
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4524
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770