DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13192 and gnb1l

DIOPT Version :9

Sequence 1:	NP_610702.1	Gene:	CG13192 / 36259	FlyBaseID:	FBgn0033653	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_001120042.1	Gene:	gnb1l / 100145018	XenbaseID:	XB-GENE-1010503	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	347	Identity:	105/347 - (30%)
Similarity:	161/347 - (46%)	Gaps:	48/347 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVLPPDPVFSLRSPDMGAVNSLCFQ------ESDRLLAGTIKGSVFLWDLQTNRSA-------- 51
            ||:..|||.|.||..| ..||||.|.      ....|.:|:..|.|.:|:|.|.||.
Frog     1 MALPSPDPKFDLRGID-AEVNSLHFSCMVQRPSQPLLFSGSSNGLVHVWNLNTRRSETVLSGHQG 64

  Fly    52 -----LHFEVGSDPITSLHHTPDRLVTQEKGGTITMFSIGGSSYVKERSIPGNHLGFCRSALHTN 111
                 ||         :|.|..:.|::|.:...|..:::......:..|:|...:|||:.:|
Frog    65 KSIYWLH---------TLFHNRELLLSQGRDLQIRTWNLAEGRREEIDSVPVESVGFCKCSL--- 117

  Fly   112 TSKTNEQLLFYPCEESS-IGVLHVTDAAAPTQILVPDDPQLPKLGSVTCFK---PFECASQLFLL 172
             .||...||..|.::|| :.||.:......:.:.:..|.|   .|...|.|   |....|.| ||
Frog   118 -LKTESCLLAMPGKDSSQVQVLDLNSKKIVSSMKLSTDNQ---WGMAMCMKLWQPISGPSPL-LL 177

  Fly   173 AGYESGHFLTWDISSSVILDVMEL-AQDATSVDYDPVTNRGIVGGPTDKLISFSY-QRSSMQMQL 235
            .|||.|....|::....::..:.. .:...|:|:|.:..||..|.....|..:|. ::.:::...
Frog   178 VGYEDGSVALWNVLEHRLMSRLTCHMEPVMSLDFDCLKARGASGSSERVLNVWSLDEQQNLKAYK 242

  Fly   236 GSELCIKNPGVNGVRIRPDQKVFASAGWDGRIRIFSWKSLRPLAVLTQHKNGGVMDLAFSSQQVA 300
            ..||.  |||::.|.:|.|:|:.|:||||.|||:|.||.::||||| |:.:..|..::||.....
Frog   243 TQELV--NPGISDVVLRQDRKILATAGWDHRIRVFGWKRMKPLAVL-QYHSAIVHCVSFSDHLTP 304

  Fly   301 MWHAPIMAAAGMDGQISLWDLY 322
              ...::||...|..||||.:|
Frog   305 --EDRLLAAGSKDHLISLWSVY 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13192	NP_610702.1	WD40	<5..321	CDD:225201	102/340 (30%)
		WD40 repeat	62..98	CDD:293791	6/35 (17%)
		WD40 repeat	103..147	CDD:293791	12/44 (27%)
		WD40 repeat	200..245	CDD:293791	11/45 (24%)
		WD40	201..>321	CDD:295369	44/120 (37%)
		WD40 repeat	247..282	CDD:293791	19/34 (56%)
gnb1l	NP_001120042.1	WD40	12..>326	CDD:225201	99/336 (29%)
		WD40	12..322	CDD:295369	97/332 (29%)
		WD40 repeat	70..107	CDD:293791	8/45 (18%)
		WD40 repeat	112..150	CDD:293791	12/41 (29%)
		WD40 repeat	159..200	CDD:293791	12/41 (29%)
		WD40 repeat	206..242	CDD:293791	8/35 (23%)
		WD40 repeat	251..287	CDD:293791	20/36 (56%)
		WD40 repeat	293..321	CDD:293791	8/29 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I10058
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41515
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4713
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1543596at2759
OrthoFinder	1	1.000	-	-		FOG0006340
OrthoInspector	1	1.000	-	-		oto103935
Panther	1	1.100	-	-	LDO	PTHR19854
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4617
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160