DRSC/TRiP Functional Genomics Resources

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Protein Alignment ths and FGF2

DIOPT Version :10

Sequence 1:NP_610701.2 Gene:ths / 36258 FlyBaseID:FBgn0033652 Length:748 Species:Drosophila melanogaster
Sequence 2:NP_001997.5 Gene:FGF2 / 2247 HGNCID:3676 Length:288 Species:Homo sapiens


Alignment Length:82 Identity:23/82 - (28%)
Similarity:35/82 - (42%) Gaps:18/82 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 KIALYAKE----------TRRYLCFNDNWRLVGMRELRDTCYFNETI-VHGYFVFRS------VV 117
            |:.|.|:|          ..|||...::.||:..:.:.|.|:|.|.: .:.|..:||      .|
Human   194 KLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYV 258

  Fly   118 DLQRRVGFTHRGKPVGP 134
            .| :|.|....|...||
Human   259 AL-KRTGQYKLGSKTGP 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
thsNP_610701.2 beta-trefoil_FGF8-like 25..148 CDD:466993 23/82 (28%)
FGF2NP_001997.5 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..133
beta-trefoil_FGF2 161..285 CDD:467000 23/82 (28%)
Cell attachment site, atypical. /evidence=ECO:0000255 179..181
Cell attachment site, atypical. /evidence=ECO:0000255 221..223 0/1 (0%)
Heparin-binding. /evidence=ECO:0000250 261..277 5/14 (36%)
Blue background indicates that the domain is not in the aligned region.

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