Protein Alignment Ir48c and glr-8

DIOPT Version :10

• Sequence 1: NP_610700.1
• Gene: Ir48c / 36257
• FlyBaseID: FBgn0033651
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 102/513 - (19%)
• Similarity: 189/513 - (36%)
• Gaps: 106/513 - (20%)

  Fly   106 NDILLIDNDEENLNSYV------DIRKAYWNAGFSQVLIYNSQQRTWSIKPYPYLQIRPTSLKEY 164
            |.|..::|..|::|..|      .:...|.:|                   |.....:..||.|
 Worm    14 NSIRTLNNILESINEKVAHPPQTSLTSDYGDA-------------------YTLSNEKHFSLSE- 58

  Fly   165 IENRNTRNLMGYPLRVLV-TNDPPHC-FVDKDELPGSPNRY-KGSIVTMLKIFADQLNATFQANP 226
                    :.|..|:::| ..:||:. :|:..:...:...| .|.::.:||....:||.|::..|
 Worm    59 --------MKGRTLKMVVPAIEPPYVNYVNFSDAAVTDKGYGPGVVMEILKEIGKRLNLTYEILP 115

  Fly   227 -----FREFRRYSTADCVQMVSDDEID--ACGSIF------IRTYTYATS-QPVRLNRVVIMAPF 277
                 :.|:...|.......:...|:|  |.|:|.      |...||... :|   ..::|.:|.
 Worm   116 ALGSTWGEYLNGSWTGAFGQLVRGEVDLLAGGAIMEYDRSVIADLTYPFQFEP---TGIMIRSPE 177

  Fly   278 GNPIEKFYYFFRPFDLYVWIGTGIIV----VYIAVMGSLLHRWHFKEWNVGQYLLLAVQTLLNRE 338
            ....:.......||...||:.|..::    |...||.::: |..::|..|..:..:.|...:..:
 Worm   178 KYEDDTLLIVTEPFSWEVWVITAAVILISGVIFLVMTNII-RKVYEEMTVTPFESIWVFFSIFVQ 241

  Fly   339 LSLP-QSSSGSKFMLLLLLFAIGFILSNLYVALLSMMLTTKLYQRPIENLADL----KAANVNIL 398
            ..|| |..|.|..:|:.|.:.....||..:...|..:........|.:|:..|    |.....|:
 Worm   242 QGLPEQPRSWSCRVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQNIDQLVRLVKQGKFEIV 306

  Fly   399 LQTHNIRPNSVYGSSE-----ELRERFLLVEESQHLEKRNGL---------DPSYAYVDSEDRMD 449
            :..::.....:...|:     :|....::..:.:::   ||:         :|.||.:.....::
 Worm   307 MDENSFTRTEMIARSKLPVYRDLWHEMIVNHKVKYV---NGIARGVAFVRANPGYALLGPMATLN 368

  Fly   450 FYLYQQ-KFLRRRRMKKLSN----PVGYTWAVQVIKQNWVLEKHYNDHVQRFFETGLQNKLVDDV 509
            ||.|.. |.:       |.|    || |. ::.::| |.:...:::..::...|.|...|.:.|.
 Worm   369 FYAYSDCKVI-------LFNDGILPV-YL-SIPLVK-NSIYSPYFSTKIREMVERGFTQKWIADY 423

  Fly   510 HELAVKAGFLHFFPTQTQTIEPLRLEDIVMAA----MVLGG---GHALAVICFLVELF 560
            ...   ..........:.||.|....|:..|.    :.|||   |.||.|..|:.:.|
 Worm   424 RSY---VAMQKINECNSTTIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir48c	NP_610700.1	HisJ	178..>280	CDD:440596	26/118 (22%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	75/378 (20%)