DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir48b and Ir67c

DIOPT Version :9

Sequence 1:	NP_610697.1	Gene:	Ir48b / 36254	FlyBaseID:	FBgn0033648	Length:	600	Species:	Drosophila melanogaster
Sequence 2:	NP_729609.1	Gene:	Ir67c / 317838	FlyBaseID:	FBgn0052058	Length:	573	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	140/573 - (24%)
Similarity:	244/573 - (42%)	Gaps:	78/573 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NDIIIELNQRLLISNNFLYCNQSDKLNEYEIKYLQHMPPISLMIFTSIESMNFTQVEYNLGADNK 91
            ||:.:::.|.  :||.|:. :.:||:     |.|......||:|..      |.....|...:..
  Fly    44 NDVELQIGQE--VSNLFVN-STADKM-----KILGRFSSHSLIIAC------FKDSTRNRTLNGV 94

  Fly    92 LFLIMGNEEPPYDFLHALNLHFQFAEYIIVIDEPVDLKKSTKWLDFVNHLWQQGYVQLLIYTSYD 156
            ..|:.|.:..|..|:...|:.|.|.:.:                       :.|::.:|.....:
  Fly    95 KELLWGLQYLPILFVVDSNMDFYFQQAL-----------------------RHGFIHVLALNFMN 136

  Fly   157 EKLYHKIIFPETVIEETLVEQYISIRGSFNNLYGYPVRVAAYNNAPRSMLYVNRWGKHIFAGFYM 221
            ..||....:|:..:.:....|.........||.|..||.......||...|.||.|:.::||:..
  Fly   137 GSLYTYKPYPKVEVHQIKDMQKFYKLTKLRNLQGQAVRTTVETMTPRCFRYRNRHGQLVYAGYMY 201

  Fly   222 RFLRAFIDARNGS----FVPVLTPSNSPGNCTLNLVNETVDVCADAL-AANPAAFSLTHGFRIAS 281
            |.::.||...||:    |..|.|.....|...|.  |..:|:....: |.....|..:|......
  Fly   202 RMVKEFISTYNGTEEHVFGNVDTVPYKEGLAALK--NGEIDMMPRIIHALEWYYFYRSHILYNIK 264

  Fly   282 ANVLVTHAKPLHSYRYLTAPFQWSVWACLV---IYVLLVVNFLSFIGWLR---SGKWEFSKYLLE 340
            ..::|..|:||....|...||:.:||..::   :|..:|      |.|:|   .|....::..::
  Fly   265 TYIMVPWAEPLPKSLYFIQPFRGTVWITIMVSFVYASIV------IWWIRYRQQGNSSLTQSFMD 323

  Fly   341 VFSSLLFSGFYLKEI----RGRERYILFGVLFIAGFVYSTEYLGLLKSMLISEVFEKQIDTFEAL 401
            |. .|||. ..|.:|    .|..:.:.|.|||:.||:.:..|...|.|.|.:.:|:.||:||:.|
  Fly   324 VL-QLLFQ-LPLSKIWHFNMGTHQVVSFIVLFVFGFMLTNLYTAQLSSYLTTGLFKSQINTFDDL 386

  Fly   402 VESNITLMVDPYDKILFAKYNMPEIL----SPIMELVSFETLLKHRNRFDQDYAYILFSDRMALY 462
            .....||:|:.:|..:.......:|:    ..|:.:.|.|.:.|||...:..|||..:.||:|..
  Fly   387 FREKRTLLVESFDAEVLHNMTKEKIIQKEFESIILITSIEEVFKHRKSLNTSYAYEAYEDRIAFE 451

  Fly   463 DYAQQFLKHP--KLLRIPID----FSFLYTGIPMRKRWFLKHHLGRAWYWAFESGLTRKLALDAD 521
            ...|::|:.|  |:|:...|    |..|..|:|..:  ...::|.|    .||||:..||..|:.
  Fly   452 LSQQRYLRVPIFKILKEVYDQRPVFVALRHGLPYVE--LFNNYLRR----IFESGIWIKLQEDSF 510

  Fly   522 FEAVRVGYLSFLITEHVEAQPLNVDYFVMPAIALAIGYILALLSFVIEMTAWR 574
            .|.:..|.:||..::..|.:..:.|::....|.|.:|:.::.::..:|:.:::
  Fly   511 LEGIASGEISFRKSKSREIKIFDKDFYFFAYILLGMGWCVSTIALFLELWSFK 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir48b	NP_610697.1	None
Ir67c	NP_729609.1	Lig_chan	288..500	CDD:278489	62/225 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010