DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13197 and DUSP11

DIOPT Version :9

Sequence 1:	NP_001286319.1	Gene:	CG13197 / 36253	FlyBaseID:	FBgn0062449	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_003575.3	Gene:	DUSP11 / 8446	HGNCID:	3066	Length:	330	Species:	Homo sapiens

Alignment Length:	340	Identity:	113/340 - (33%)
Similarity:	157/340 - (46%)	Gaps:	56/340 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IPDRWLKYKPIGDRVPGTRFIAFKVPLNQHVNAKVKENLRLAPESLLQIV----PDMGLIIDLTN 65
            ||:||..|.|:|.|:||||||||||||.:....|:......:|..|...:    .::|||||||.
Human    31 IPERWKDYLPVGQRMPGTRFIAFKVPLQKSFEKKLAPEECFSPLDLFNKIREQNEELGLIIDLTY 95

  Fly    66 TNRYYHPSAITNHDVLHQKLMIPGKQTPSHKLAQRFCAFVTDFLERNADNDKLIGVHCTHGVNRT 130
            |.|||.|..:. ..|.:.|:...|.|.|..:...:|...|..||:.|.|||||||||||||:|||
Human    96 TQRYYKPEDLP-ETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHCTHGLNRT 159

  Fly   131 GYLICYFMISVMNMSPEEAIQTFSLARGHEIERDNYLSSLKTLPNRETVTKLAATERRSSTIDNW 195
            |||||.::|.|..:.|::||:.|:..|||.:||.||:..|:..|.|:                ||
Human   160 GYLICRYLIDVEGVRPDDAIELFNRCRGHCLERQNYIEDLQNGPIRK----------------NW 208

  Fly   196 RQPIDYQSERDLHQKNNHRLSKVLKTKSYQEHDDCRRRDRWNQHPYARNHRPHPVEEQRRIQSNR 260
            ...:...|:   .:.:.|.:..|       .:...::..|:|.|....:..|.....|.:.....
Human   209 NSSVPRSSD---FEDSAHLMQPV-------HNKPVKQGPRYNLHQIQGHSAPRHFHTQTQSLQQS 263

  Fly   261 SRDGYQQGSNQHPYSRNHRPHPVEEQYRIQSNRSGGGYQQGSISYQQEPHQRYQRNWDYSRRNYS 325
            .|   :...|.|.|.|:|.|.|         ...|..|.          |:||  :|:. :.|.|
Human   264 VR---KFSENPHVYQRHHLPPP---------GPPGEDYS----------HRRY--SWNV-KPNAS 303

  Fly   326 ERNYSERNWSERNYS 340
            ......|.|...|||
Human   304 RAAQDRRRWYPYNYS 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13197	NP_001286319.1	PTPc	43..171	CDD:304379	58/131 (44%)
DUSP11	NP_003575.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	117	1.000	Domainoid score	I5935
eggNOG	1	0.900	-	-		E1_COG5226
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4091
Isobase	1	0.950	-	0	Normalized mean entropy	S5132
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1544021at2759
OrthoFinder	1	1.000	-	-		FOG0005200
OrthoInspector	1	1.000	-	-		oto91295
orthoMCL	1	0.900	-	-		OOG6_108715
Panther	1	1.100	-	-	LDO	PTHR10367
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3925
SonicParanoid	1	1.000	-	-		X4820
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.810