DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13197 and Dusp11

DIOPT Version :9

Sequence 1:	NP_001286319.1	Gene:	CG13197 / 36253	FlyBaseID:	FBgn0062449	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001020821.1	Gene:	Dusp11 / 297412	RGDID:	1307038	Length:	326	Species:	Rattus norvegicus

Alignment Length:	342	Identity:	112/342 - (32%)
Similarity:	164/342 - (47%)	Gaps:	71/342 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IPDRWLKYKPIGDRVPGTRFIAFKVPLNQHVNAKVKENLRLAPESLLQIV----PDMGLIIDLTN 65
            ||:||..|.|:|.|:||||||||||||.:...||:......:|..|...:    .::|||||||.
  Rat    29 IPERWKDYLPVGQRMPGTRFIAFKVPLQKKFEAKLMPEECFSPLDLFNKIQEQNEELGLIIDLTY 93

  Fly    66 TNRYYH----PSAITNHDVLHQKLMIPGKQTPSHKLAQRFCAFVTDFLERNADNDKLIGVHCTHG 126
            |.|||.    |..|:     :.|::..|.|.|......:|.:.|.:||:||.:||||||||||||
  Rat    94 TQRYYKVEDLPKTIS-----YIKILTVGHQVPDSGTIFQFKSAVKEFLKRNKNNDKLIGVHCTHG 153

  Fly   127 VNRTGYLICYFMISVMNMSPEEAIQTFSLARGHEIERDNYLSSLKTLPNRETVTKLAATERRSST 191
            :||||||||.::|.|..|.|::||:.|:..|||.|||.||:.:|:   .|.......|:..||..
  Rat   154 LNRTGYLICRYLIDVEGMRPDDAIELFNRCRGHCIERQNYIENLQ---KRRVRKNQNASASRSGG 215

  Fly   192 IDNWRQPIDYQSERDLHQKNNHRLSKVLKTKSYQEHDDCRRRDRWNQHPYARNHRPHPVEEQRRI 256
            :::                :.|...:|..|..           ..|:.| .::.|...:|..:.:
  Rat   216 LED----------------SAHLTEQVHTTNK-----------PVNKGP-KKSRRGGHLESSQHV 252

  Fly   257 QSNRSRDGYQQGS-NQHPYSRNHRPHPVEEQYRIQSNRSGGGYQQGSISYQQEP-------HQR- 312
            |:..|...:::.| ||..|.|...|.|         ..:|..|.|....:...|       |::
  Rat   253 QTQSSAYSFRKWSQNQSVYQRGFVPPP---------GPAGEDYSQRRFFWSMRPNGSQATHHKKW 308

  Fly   313 ----YQR-----NWDYS 320
                |||     :|:::
  Rat   309 IAASYQRPFYPASWEWN 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13197	NP_001286319.1	PTPc	43..171	CDD:304379	60/135 (44%)
Dusp11	NP_001020821.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		PTPc	77..194	CDD:304379	57/121 (47%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:O75319	151..156		3/4 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..258		12/85 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5743
eggNOG	1	0.900	-	-		E1_COG5226
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1544021at2759
OrthoFinder	1	1.000	-	-		FOG0005200
OrthoInspector	1	1.000	-	-		oto98379
orthoMCL	1	0.900	-	-		OOG6_108715
Panther	1	1.100	-	-	LDO	PTHR10367
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4820
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820