Protein Alignment wal and ETFA

DIOPT Version :10

• Sequence 1: NP_476975.1
• Gene: wal / 36252
• FlyBaseID: FBgn0010516
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_000117.1
• Gene: ETFA / 2108
• HGNCID: 3481
• Length: 333
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 229/328 - (69%)
• Similarity: 271/328 - (82%)
• Gaps: 2/328 - (0%)

  Fly     1 MF-ASNTRNLMRSSILQRCKSTLVVAEHNNEVLNPITLNTISAAKKIGGDVTVLVAGTKCGPASE 64
            || |:....|.|::.|.|.:||||:|||.|:.|.|||||||:||.::||:|:.|||||||...::
Human     1 MFRAAAPGQLRRAASLLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQ 65

  Fly    65 ALSKVDGVTKVLVAENAAFNGFTAESLTPLVLAAQSQFKFTHILAGASAFGKNVLPRVAAKLDVS 129
            .|.||.|:.|||||::..:.|...|.||||:||.|.||.:|||.|||||||||:||||||||:|:
Human    66 DLCKVAGIAKVLVAQHDVYKGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVA 130

  Fly   130 PISEIIDVKSDDTFVRTIYAGNAILTLKSKDAVKVITVRSTNFPPAATSGGSGAVEQAPAGDFAS 194
            |||:||.:||.||||||||||||:.|:|..:.|||.:||.|:|..|||||||.:.|:| :.....
Human   131 PISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFDAAATSGGSASSEKA-SSTSPV 194

  Fly   195 SLSEFVSQELTKSDRPELAGAKVIVSGGRGLKSGDNFKLLYDLADKFGAAVGASRAAVDAGFVPN 259
            .:||::.|:|||||||||.||||:||||||||||:||||||||||:..|||||||||||||||||
Human   195 EISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPN 259

  Fly   260 DLQIGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADIGIVADLFKAVP 324
            |:|:|||||||||||||||||||||||||||||||||||||||||||||||||.||||||||.||
Human   260 DMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVP 324

  Fly   325 ELT 327
            |:|
Human   325 EMT 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wal	NP_476975.1	FixB	20..330	CDD:441628	222/308 (72%)
ETFA	NP_000117.1	Domain I. /evidence=ECO:0000269|PubMed:8962055	20..204		109/184 (59%)
		FixB	21..332	CDD:441628	222/308 (72%)
		Domain II. /evidence=ECO:0000269|PubMed:8962055	205..333		112/123 (91%)