Protein Alignment Buffy and BCL2A1

DIOPT Version :10

• Sequence 1: NP_523702.1
• Gene: Buffy / 36251
• FlyBaseID: FBgn0040491
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_004040.1
• Gene: BCL2A1 / 597
• HGNCID: 991
• Length: 175
• Species: Homo sapiens
• Alignment Length: 108
• Identity: 29/108 - (26%)
• Similarity: 48/108 - (44%)
• Gaps: 19/108 - (17%)

  Fly   173 DAVSLLLGAVGRELFR--VE-------ITWSKVISLFAIAGGLSVDCVRQGHPEYLP------KL 222
            |.|:::.....|.||.  :|       |.|.:::::||..|.|....:||   :..|      ::
Human    57 DNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQ---QIAPDVDTYKEI 118

  Fly   223 MESVSEVIEDELVPWINENGGW-SGINTHVLPTTNSLNPLEWT 264
            ...|:|.|.:....||.:|||| :|......|.:..:..||.|
Human   119 SYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVT 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Buffy	NP_523702.1	Bcl-2_like	99..250	CDD:132900	25/92 (27%)
BCL2A1	NP_004040.1	Bcl-2_like	10..146	CDD:132900	25/91 (27%)
		BH1	77..97		4/19 (21%)
		BH2	132..147		7/14 (50%)