DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Buffy and Debcl

DIOPT Version :9

Sequence 1:	NP_523702.1	Gene:	Buffy / 36251	FlyBaseID:	FBgn0040491	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	110/282 - (39%)
Similarity:	161/282 - (57%)	Gaps:	39/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GTSYPTNNDNFSNGFPMATTQSERLLQAQNRRKFSFPATLHSASLLEVGGGPKETTRRRLSNVSD 67
            |...|.:..|.|||                       .:||:       |||  .||...::...
  Fly    49 GAGGPGSVPNPSNG-----------------------RSLHA-------GGP--MTRAASTSSLA 81

  Fly    68 AVTRKLSYTIGWKAAQIPAQDIISQGRCLCGHYIKRRLRRSGLFNKKLGLQRIRSILGSTSMGIV 132
            :.||.::....:|      .|||:||:||||.||:.||||:|:.|:|: .||:|:||...|..:|
  Fly    82 SSTRTMTNYQEYK------MDIINQGKCLCGQYIRARLRRAGVLNRKV-TQRLRNILDPGSSHVV 139

  Fly   133 RDVFPAVQVLGDELERMHPRIYNGVARQICRNPGGEFHTPDAVSLLLGAVGRELFRVEITWSKVI 197
            .:||||:..:|:||||||||:|..::||:.|.|.||....|...:||..|.::|||..|||.|:|
  Fly   140 YEVFPALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKII 204

  Fly   198 SLFAIAGGLSVDCVRQGHPEYLPKLMESVSEVIEDELVPWINENGGWSGINTHVLPTTNSLNPLE 262
            |:||:.||.::|||||||.:||..|::.::|:|||:||.|:.:||||.|::.|:.|.......|.
  Fly   205 SIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEIIEDDLVYWLIDNGGWLGLSRHIRPRVGEFTFLG 269

  Fly   263 WTTLVIGVVFGLILVFMILRFI 284
            |.||.:.:..|..:|..:.|.|
  Fly   270 WLTLFVTISAGAYMVSNVCRRI 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Buffy	NP_523702.1	Bcl-2_like	99..250	CDD:132900	75/150 (50%)
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	75/150 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444245
Domainoid	1	1.000	90	1.000	Domainoid score	I7754
eggNOG	1	0.900	-	-		E1_KOG4728
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4946
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278637at2759
OrthoFinder	1	1.000	-	-		FOG0005475
OrthoInspector	1	1.000	-	-		mtm6365
orthoMCL	1	0.900	-	-		OOG6_108286
Panther	1	1.100	-	-	P	PTHR11256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3895
	11	10.800