Protein Alignment Buffy and Bcl2l2

DIOPT Version :10

• Sequence 1: NP_523702.1
• Gene: Buffy / 36251
• FlyBaseID: FBgn0040491
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_031563.1
• Gene: Bcl2l2 / 12050
• MGIID: 108052
• Length: 193
• Species: Mus musculus
• Alignment Length: 194
• Identity: 41/194 - (21%)
• Similarity: 73/194 - (37%)
• Gaps: 31/194 - (15%)

  Fly    94 RCLCGHYIKRRLRRSGLFNKKLGLQRIRSILGS-TSMGIVRD-VFPAVQVLGDELERMHPRIYNG 156
            |.|...::..:||:.|.            :.|: ...|...| :..|::..|||.|....|.::.
Mouse    11 RALVADFVGYKLRQKGY------------VCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSD 63

  Fly   157 VARQICRNPGGEFH-TPDAVSLLLGAVGRELFRVEITWSKVISLFAIAGGLSVDCVRQGHPEYLP 220
            :|.|:        | ||.:.......|..|||:....|.::::.|.....|..:.|.:.....:.
Mouse    64 LAAQL--------HVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG 120

  Fly   221 KLMESVSEVIEDELVPWINENGGWSGINT----HVLPTTNSLNPLEW----TTLVIGVVFGLIL 276
            ::.:.:...:|..|..||:.:|||:....    ..|.....|....|    |.|...|..|.::
Mouse   121 QVQDWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALV 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Buffy	NP_523702.1	Bcl-2_like	99..250	CDD:132900	32/157 (20%)
Bcl2l2	NP_031563.1	BH4	9..29		5/29 (17%)
		bcl-2	11..193	CDD:273308	41/194 (21%)
		BH1	85..104		5/18 (28%)
		BH2	136..151		5/14 (36%)