Protein Alignment INHBB and scw

DIOPT Version :9

• Sequence 1: NP_002184.2
• Gene: INHBB / 3625
• HGNCID: 6067
• Length: 407
• Species: Homo sapiens
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 93/414 - (22%)
• Similarity: 158/414 - (38%)
• Gaps: 116/414 - (28%)

Human    62 RRP--EELGRVD----GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVT------------ALR 108
            :||  |::..:|    ||           |.:.:..||:.::..|..:..            .|.
  Fly    33 KRPLSEQMEMIDILDLGD-----------RPRRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLH 86

Human   109 KLHAGKVREDGRVEIPHLDGHASPGADGQERVS--EIISFAETDGLASSRVR---------LYF- 161
            :.|...:.:|..:.          ..|.||..|  .|::|       |||::         ::.
  Fly    87 QRHKRSLDDDILIS----------NEDRQEIASCNSILTF-------SSRLKPEQLDNELDMHIT 134

Human   162 FISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRS-- 224
            |.:|:...:|.:|||.|.:|.:  |.::::  |....|.||.:.....|....:...|:...|
  Fly   135 FNTNDVPVDLSLVQAMLRIYKQ--PSLVDR--RANFTVSVYRKLDNRQDFSYRILGSVNTTSSQR 195

Human   225 GWHTFPLTEAI------QALFERGERRLNL-DVQCDSCQELAVVPVFVDPGEESHRPFVV----- 277
            ||..|.||:.:      :.|..|.|.|::: |.|..:.....|.|   .....|..||:|
  Fly   196 GWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTP---QASRTSLEPFIVGYFNG 257

Human   278 ------VQARLGDSRHRIR-KRGLE---CDGRT---------------NLCCRQQFFIDFRLIGW 317
                  :|        ::| ||.||   ..|.:               ..|.|..|.:||:.:..
  Fly   258 PELLVKIQ--------KLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHM 314

Human   318 NDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSM 382
            ::|:|||..:...:|.|.| .:..|...:|:: |..|  |..|....|.....||:||.|..:::
  Fly   315 HNWVIAPKKFEAYFCGGGC-NFPLGTKMNATN-HAIV--QTLMHLKQPHLPKPCCVPTVLGAITI 375

Human   383 LYFDDEYNIVKRDVPNMIVEECGC 406
            |.:.:|..|........:.:||||
  Fly   376 LRYLNEDIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INHBB	NP_002184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..62		93/414 (22%)
		TGFb_propeptide	57..278	CDD:279078	55/265 (21%)
		TGFB	303..406	CDD:214556	29/102 (28%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	52/249 (21%)
		TGFB	300..400	CDD:214556	31/104 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810