Protein Alignment Tret1-2 and SIT1

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_010849.3
• Gene: SIT1 / 856644
• SGDID: S000000791
• Length: 628
• Species: Saccharomyces cerevisiae
• Alignment Length: 551
• Identity: 104/551 - (18%)
• Similarity: 164/551 - (29%)
• Gaps: 240/551 - (43%)

  Fly    27 SQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGP 91
            |.:....|:.:.|::.     |:...::......||.|.        |||......|.|.|.
Yeast   130 SDIFGRFSIMIVSIIF-----YSMGTIIESQAVNITRFA--------VGGCFYQLGLTGIIL--- 178

  Fly    92 LIEYLG--------RRSTILATAVPFIVSS------------------------LLIACAVNVIM 124
            ::|.:.        |...:...|:|||:::                        |.:||....|.
Yeast   179 ILEVIASDFSNLNWRLLALFIPALPFIINTWISGNVTSAIDANWKWGIGMWAFILPLACIPLGIC 243

  Fly   125 ILCGRFLT---------------------GFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGN 168
            :|..|:|.                     .||:.||...|.:
Yeast   244 MLHMRYLARKHAKDRLKPEFEALNKLKWKSFCIDIAFWKLDI----------------------- 285

  Fly   169 IGILVCYVAGSFMNWSMLAFLGAALPVPFLI----------LMIIIPETPRWFVNRGQEERARKA 223
            ||:|:..|           |.|..| |||.:          ..||:||...|.|
Yeast   286 IGMLLITV-----------FFGCVL-VPFTLAGGLKEEWKTAHIIVPEVIGWVV----------- 327

  Fly   224 LKWLRGKEADVEP-----ELKELMQSQADADRQATQNTCLELFKRNNLKP--------LSISLGL 275
                      |.|     |:|                     :.|:.|.|        :..:|.:
Yeast   328 ----------VLPLYMLWEIK---------------------YSRHPLTPWDLIQDRGIFFALLI 361

  Fly   276 MFFQQFSG-INAVIFYTVQI------FKDAGSTIDSNLS--TIIVGVVNFFATFMGIILIDRLGR 331
            .||..|:. :.....|||.:      .|.| :.|.|..|  ::|||      |.:|.|||.....
Yeast   362 AFFINFNWYMQGDYMYTVLVVAVHESIKSA-TRITSLYSFVSVIVG------TILGFILIKVRRT 419

  Fly   332 KILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEIL 396
            |..:.......||:..:|..:     .|...:|.|.:...|    :|||  |.|...::....|.
Yeast   420 KPFIIFGISCWIVSFGLLVHY-----RGDSGAHSGIIGSLC----LLGF--GAGSFTYVTQASIQ 473

  Fly   397 PAKIRGPAASVVTAFNWFCTF---------------------VVTKTFQDLTVAMGAHGAFWLF- 439
            .:.......:|||:. :..|:                     .::|...|.|:|..|:|:.:.|
Yeast   474 ASAKTHARMAVVTSL-YLATYNIGSAFGSSVSGAVWTNILPKEISKRISDPTLAAQAYGSPFTFI 537

  Fly   440 ---------------------GAICIVGLFF 449
                                 ..:||:||.|
Yeast   538 TTYTWGTPERIALVMSYRYVQKILCIIGLVF 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	103/549 (19%)
SIT1	NP_010849.3	MFS_ARN_like	70..582	CDD:340880	104/551 (19%)