Protein Alignment Tret1-2 and ITR2

DIOPT Version :9

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_014538.2
• Gene: ITR2 / 854050
• SGDID: S000005463
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 477
• Identity: 125/477 - (26%)
• Similarity: 218/477 - (45%)
• Gaps: 31/477 - (6%)

  Fly    18 DGLKANFTFSQVLAALSV------SLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGG 76
            |......||:|.::...:      |:...:.|:.:.|.|.||:|: :|.:.:..:|......:..
Yeast    93 DDTSVIITFNQSISPFIITLTFVASISGFMFGYDTGYISSALISI-NRDLDNKVLTYGEKELITA 156

  Fly    77 IMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASL 141
            ...|.||...:..|...:..|||..::.:.:.|::.::|...|.....:..||.:.||.|||.||
Yeast   157 ATSLGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSL 221

  Fly   142 SLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-----WSMLAFLGAALPVPFLILM 201
            ..|:::.|.....:||.|.::.:.....|.|:.|..|:.:|     |.:|..|.....|......
Yeast   222 ISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFF 286

  Fly   202 IIIPETPRWFVNRGQEERARKALK--WLRGKEADVEPELKEL--MQSQADADRQATQ--NTCLEL 260
            ..:|:|||::|.:|..:||:..||  ::..::..::.:::||  :..........|:  |...||
Yeast   287 CFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKEL 351

  Fly   261 FK-RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGII 324
            .. .:|.:.|.|..||...|||:|.|::::::..||:..|....|.:|.|:.| .||..|.:...
Yeast   352 HTVPSNFRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSG-TNFVFTLIAFF 415

  Fly   325 LIDRLGRKILLYVSDIAMIVTLSILGGFFY---CKAHGPDV-------SHLGWLPLTCFVIYILG 379
            .||::||:.:|.:....|.|.|.|....|:   .|.:|.|.       |..|.:.:...::|...
Yeast   416 CIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKFNGADAVVASDGFSSWGIVIIVFIIVYAAF 480

  Fly   380 FSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICI 444
            ::||.|.:|| ...|:.|..:||...|..||.||..:.|:..||..:...:...|.|..|..:..
Yeast   481 YALGIGTVPW-QQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVAC 544

  Fly   445 VGLFFVIIFVPETRGKSLEEIE 466
            :...|.....||..|..|||::
Yeast   545 LSTIFCYFCYPELSGLELEEVQ 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	121/464 (26%)
		MFS	33..454	CDD:119392	115/448 (26%)
ITR2	NP_014538.2	MFS_HMIT_like	115..556	CDD:340918	115/443 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342407
Domainoid	1	1.000	166	1.000	Domainoid score	I806
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740