Protein Alignment Tret1-2 and ITR1

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_010785.1
• Gene: ITR1 / 852108
• SGDID: S000002905
• Length: 584
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 135/490 - (27%)
• Similarity: 228/490 - (46%)
• Gaps: 57/490 - (11%)

  Fly    18 DGLKANFTFSQVLAALSV------SLCSLVVGFVSAYTSPALVSM---TDRTITSF---EVTKDA 70
            |......||:|.|:...:      |:...:.|:.:.|.|.||:|:   .|..:.::   |:...|
Yeast    70 DDTSVMITFNQSLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAA 134

  Fly    71 GSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFC 135
            .|       |.||...|..|...:..||:..::.:.:.|::.::|...|.....:..||.:.||.
Yeast   135 TS-------LGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFG 192

  Fly   136 VGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN-----WSMLAFLGAALPV 195
            |||.||..|:::.|.....:||.|.::.:.....|.||.|..|:.:|     |.:|  :|.:| :
Yeast   193 VGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRIL--VGLSL-I 254

  Fly   196 PFLI---LMIIIPETPRWFVNRGQEERARKALK--WLRGKEADVEPELKELMQ-SQADADRQATQ 254
            |..:   .:..:|:|||::|.:|...||.:.||  :....|..:|.:::||:. :|:...:...:
Yeast   255 PTAVQFTCLCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPE 319

  Fly   255 ---NTCLELFK-RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVN 315
               ||..||.. .:||:.|.|..||...|||:|.|::::::..||:..|....|.:|.|:.| .|
Yeast   320 KVWNTIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSG-TN 383

  Fly   316 FFATFMGIILIDRLGRKILLYVSDIAM---IVTLSILGGFFYCKAHG-------PDVSHLGWLPL 370
            |..|.:....||::||:.:|.:....|   :|..||...|...|..|       ...|..|.:.:
Yeast   384 FIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVII 448

  Fly   371 TCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTF----QDLTVAMG 431
            ...:::...::||.|.:|| ...|:.|..:||...|..||.||..:.|:..||    |::|.|
Yeast   449 VFIIVFAAFYALGIGTVPW-QQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPA-- 510

  Fly   432 AHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIE 466
              |.|..|..:..:...|.....||..|..|||::
Yeast   511 --GTFAFFAGLSCLSTIFCYFCYPELSGLELEEVQ 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	129/475 (27%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	124/456 (27%)