Protein Alignment Tret1-2 and RGT2

DIOPT Version :9

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_010143.1
• Gene: RGT2 / 851417
• SGDID: S000002297
• Length: 763
• Species: Saccharomyces cerevisiae
• Alignment Length: 505
• Identity: 136/505 - (26%)
• Similarity: 241/505 - (47%)
• Gaps: 78/505 - (15%)

  Fly    27 SQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTIT--------SFEVTKDAGSWVGGIMPLAAL 83
            |.|::.| |.:...|.||:..|.:..:.|:||....        |:..|......| ..:.|...
Yeast    95 SNVMSVL-VGIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQIAILV-SFLSLGTF 157

  Fly    84 AGGITGGPLIEYLGRRSTIL-ATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYL 147
            .|.:....:.:..||:.||: :|||.|.:.:.|...:..:::::.||.::|..:||.|..:|:|.
Yeast   158 FGALIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVVPLYQ 222

  Fly   148 GETLQPEVRG----------TLGLLPTALGNIG-------------ILVCYVAGSFMNWSMLAFL 189
            .|..|..:||          |:|||.::..:.|             |.:.||      ||.:..:
Yeast   223 AEAAQKNLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRIPIGLQYV------WSSILAV 281

  Fly   190 GAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQAT- 253
            |          ||.:||:||::|.:.:..:|.|:|.:|||...:....|:||::.:|..|.:|:
Yeast   282 G----------MIFLPESPRYYVLKDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEASF 336

  Fly   254 -QNTCLELFKRNNLKPLSI-----SLGLMFFQQFSGINAVIFYTVQIFKDAGSTID-SNLSTIIV 311
             .:|.|:.||.:..:|..|     .:.:..|||.||||.:.:|.|..|.:.|  :| |.|.:.|.
Yeast   337 GPSTLLDCFKTSENRPKQILRIFTGIAIQAFQQASGINFIFYYGVNFFNNTG--VDNSYLVSFIS 399

  Fly   312 GVVNFFATFMGIILIDRLGRKILLYVSDIAMIV---TLSILGGFFYCKAHGPDVSHLGWLPLTCF 373
            ..||...:..|:.|:||:||:.:|....:.|.:   .::|:|     .:.|..|. ...:.:...
Yeast   400 YAVNVAFSIPGMYLVDRIGRRPVLLAGGVIMAIANLVIAIVG-----VSEGKTVV-ASKIMIAFI 458

  Fly   374 VIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTF---VVTKTFQDL---TVAMGA 432
            .::|..||..:|.:.|::..|:.|..:|....::..|.||...|   ::|....|:   |.:||.
Yeast   459 CLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGP 523

  Fly   433 HGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVPMSSVVNIK 482
            . .|:::|.:.:|.:..|...|.||||.:||||: ::..:.| :||::.|
Yeast   524 K-IFFIWGGLNVVAVIVVYFAVYETRGLTLEEID-ELFRKAP-NSVISSK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	130/484 (27%)
		MFS	33..454	CDD:119392	121/469 (26%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	130/486 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342616
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R490
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	7	6.670