DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-2 and ERDL6

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_177658.1	Gene:	ERDL6 / 843859	AraportID:	AT1G75220	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	171/460 - (37%)
Similarity:	257/460 - (55%)	Gaps:	34/460 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SQVL--AALSVSLCSLVV-------GFVSAYTSPALVSMTDRTITSFEVTKDAG------SWVGG 76
            |||:  :::||..|.|:|       ||...|:||          |...:|||.|      |..|.
plant    38 SQVIRDSSISVLACVLIVALGPIQFGFTCGYSSP----------TQAAITKDLGLTVSEYSVFGS 92

  Fly    77 IMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASL 141
            :..:.|:.|.|..|.:.||:||:.:::..|:|.|:..|.|:.|.:...:..||.|.||.|||.|.
plant    93 LSNVGAMVGAIASGQIAEYIGRKGSLMIAAIPNIIGWLCISFAKDTSFLYMGRLLEGFGVGIISY 157

  Fly   142 SLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLIL-MIIIP 205
            ::|||:.|.....:||.||.:......|||::.|:.|.|:.|.:||.|| .||...||. :..||
plant   158 TVPVYIAEIAPQNMRGGLGSVNQLSVTIGIMLAYLLGLFVPWRILAVLG-ILPCTLLIPGLFFIP 221

  Fly   206 ETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLS 270
            |:|||....|..:....:|:.|||.|.|:..|:.|:.:|.|.:.::.|.. .::|.:|....||.
plant   222 ESPRWLAKMGMTDEFETSLQVLRGFETDITVEVNEIKRSVASSTKRNTVR-FVDLKRRRYYFPLM 285

  Fly   271 ISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILL 335
            :.:||:..||..|||.|:||:..||:.||.| .||.:|..||.:...||.:...|:|:.||::||
plant   286 VGIGLLVLQQLGGINGVLFYSSTIFESAGVT-SSNAATFGVGAIQVVATAISTWLVDKAGRRLLL 349

  Fly   336 YVSDIAMIVTLSILGGFFYCKAH-GPDVSHLGWLPLTC---FVIYILGFSLGFGPIPWLMMGEIL 396
            .:|.:.|.::|.|:...||.|.. .||.....||.:..   .|..::.||||.||||||:|.|||
plant   350 TISSVGMTISLVIVAAAFYLKEFVSPDSDMYSWLSILSVVGVVAMVVFFSLGMGPIPWLIMSEIL 414

  Fly   397 PAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKS 461
            |..|:|.|.|:.|..|||.::::|.| .:|.:|..:.|.|.|:|.:|...:.||.::||||:||:
plant   415 PVNIKGLAGSIATLANWFFSWLITMT-ANLLLAWSSGGTFTLYGLVCAFTVVFVTLWVPETKGKT 478

  Fly   462 LEEIE 466
            |||::
plant   479 LEELQ 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	168/454 (37%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	159/438 (36%)
ERDL6	NP_177658.1	MFS_GLUT6_8_Class3_like	49..481	CDD:340916	164/445 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69170
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830