DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and INT2

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_174313.1	Gene:	INT2 / 839902	AraportID:	AT1G30220	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	159/548 - (29%)
Similarity:	253/548 - (46%)	Gaps:	122/548 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGIT----GGPL 92
            |.|..:..|:.|:.:...|.||:.:.|    .|: :.|..:|:..::...|:||.|.    ||..
plant    32 AFSAGIGGLLFGYDTGVISGALLYIRD----DFK-SVDRNTWLQEMIVSMAVAGAIVGAAIGGWA 91

  Fly    93 IEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRG 157
            .:.|||||.||.....|::.::::|.|.|..:::.||...|..||:||::.|:|:.|....::||
plant    92 NDKLGRRSAILMADFLFLLGAIIMAAAPNPSLLVVGRVFVGLGVGMASMTAPLYISEASPAKIRG 156

  Fly   158 TLGLLPTALGNIGILVCYVAGSFMNWSM-LAF----------LGAALPVPFL---ILMIIIPETP 208
            .|      :...|.|:  ..|.|:::.: |||          ||.| .:|.|   :||..:||:|
plant   157 AL------VSTNGFLI--TGGQFLSYLINLAFTDVTGTWRWMLGIA-GIPALLQFVLMFTLPESP 212

  Fly   209 RWFVNRGQEERARKALKWLRGKEADVEPE---LKELMQSQADADRQATQNTCLELFKRNNL-KPL 269
            ||...:|:||.|:..|:.:...| |||.|   ||:.::::...:..:.:...::|.|...: :.|
plant   213 RWLYRKGREEEAKAILRRIYSAE-DVEQEIRALKDSVETEILEEGSSEKINMIKLCKAKTVRRGL 276

  Fly   270 SISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVV----NFFATFMGIILIDRLG 330
            ...:||..||||.|||.|::|:..|.:.||  ..||.:.:::.:|    |.|.:.:.|..|||:|
plant   277 IAGVGLQVFQQFVGINTVMYYSPTIVQLAG--FASNRTALLLSLVTAGLNAFGSIISIYFIDRIG 339

  Fly   331 RKILLYVSDIAMIVTLSILGGFFY-CKAHGPDVSHL----------------------------- 365
            ||.||.:|...:|::|.||.|.|| ...|.|.:|.|
plant   340 RKKLLIISLFGVIISLGILTGVFYEAATHAPAISSLETQRFNNISCPDYKSAMNTNAWDCMTCLK 404

  Fly   366 ------------------------------------------------GWLPLTCFVIYILGFSL 382
                                                            ||..|....:||:.||.
plant   405 ASSPSCGYCSSPIGKEHPGACWISDDSVKDLCHNENRLWYTRGCPSNFGWFALLGLGLYIIFFSP 469

  Fly   383 GFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGL 447
            |.|.:||::..||.|.:.||....:....||....:|.::|..||.|:|....|.:||.|.::.|
plant   470 GMGTVPWIVNSEIYPLRFRGICGGIAATANWISNLIVAQSFLSLTEAIGTSWTFLIFGVISVIAL 534

  Fly   448 FFVIIFVPETRGKSLEEIERKMMGRVPM 475
            .||::.||||:|..:|||| ||:.|..|
plant   535 LFVMVCVPETKGMPMEEIE-KMLERRSM 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	154/538 (29%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	145/524 (28%)
INT2	NP_174313.1	SP	25..552	CDD:273317	152/536 (28%)
INT2	NP_174313.1	MFS	33..541	CDD:119392	145/524 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810