DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT5G18840

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_568367.1	Gene:	AT5G18840 / 832002	AraportID:	AT5G18840	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	458	Identity:	148/458 - (32%)
Similarity:	232/458 - (50%)	Gaps:	34/458 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 NFTFSQVLAALSVSLC-SLVVGFVSAYTSPALVSM-TDRTITSFEVTKDAGSWVGGIMPLAALAG 85
            |.::..||.:..|::| |...|....|::|...|: .|..::..|.     |..|.|:.:.|:.|
plant    38 NESYLMVLFSTFVAVCGSFEFGSCVGYSAPTQSSIRQDLNLSLAEF-----SMFGSILTIGAMLG 97

  Fly    86 GITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGET 150
            .:..|.:.::.||:..:..:|...|...|.:......:::..|||.||:.:|:.|..:|||:.|.
plant    98 AVMSGKISDFSGRKGAMRTSACFCITGWLAVFFTKGALLLDVGRFFTGYGIGVFSYVVPVYIAEI 162

  Fly   151 LQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRG 215
            ....:||.|..|...:..||..|.::.||.::|..||..|.|..:..|..:..|||:|||....|
plant   163 SPKNLRGGLTTLNQLMIVIGSSVSFLIGSLISWKTLALTGLAPCIVLLFGLCFIPESPRWLAKAG 227

  Fly   216 QEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPL-------SISL 273
            .|:..|.||:.||||:||:        .::||..:.:.|  .||:..:..::.|       |:.:
plant   228 HEKEFRVALQKLRGKDADI--------TNEADGIQVSIQ--ALEILPKARIQDLVSKKYGRSVII 282

  Fly   274 G--LMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLY 336
            |  ||.||||.|||.:.||..:.|..||.| ...|.||.:..|....|.:|.||||:.||:.|:.
plant   283 GVSLMVFQQFVGINGIGFYASETFVKAGFT-SGKLGTIAIACVQVPITVLGTILIDKSGRRPLIM 346

  Fly   337 VSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTC---FVIYILGFSLGFGPIPWLMMGEILPA 398
            :|...:.:...:.|..|..|...   ..|.|:|...   .:||:..||:|.||:||::|.||.|.
plant   347 ISAGGIFLGCILTGTSFLLKGQS---LLLEWVPSLAVGGVLIYVAAFSIGMGPVPWVIMSEIFPI 408

  Fly   399 KIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLE 463
            .::|.|.|:|...||...:.|:.||..| ::..:.|.|:|:.|.....:.||...||||:||:||
plant   409 NVKGIAGSLVVLVNWSGAWAVSYTFNFL-MSWSSPGTFYLYSAFAAATIIFVAKMVPETKGKTLE 472

  Fly   464 EIE 466
            ||:
plant   473 EIQ 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	145/450 (32%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	135/434 (31%)
AT5G18840	NP_568367.1	MFS_GLUT6_8_Class3_like	45..473	CDD:340916	143/447 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.930