DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and INT4

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001328028.1	Gene:	INT4 / 827346	AraportID:	AT4G16480	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	554	Identity:	144/554 - (25%)
Similarity:	234/554 - (42%)	Gaps:	120/554 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGI----TGGPL 92
            |||..:..|:.|:.:...|.||:.:.:    .|:.. |..:|:...:...|:||.|    .||.:
plant    31 ALSAGIGGLLFGYDTGVISGALLFIKE----DFDEV-DKKTWLQSTIVSMAVAGAIVGAAVGGWI 90

  Fly    93 IEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRG 157
            .:..|||.:||...|.|::.::::|.|....:|:.||...||.||:||::.|:|:.|.....:||
plant    91 NDKFGRRMSILIADVLFLIGAIVMAFAPAPWVIIVGRIFVGFGVGMASMTSPLYISEASPARIRG 155

  Fly   158 TL----GLLPTALGN-----IGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVN 213
            .|    |||.|. |.     |.:...:..|:: .| ||...|....|.| :||:.:||:|||...
plant   156 ALVSTNGLLITG-GQFFSYLINLAFVHTPGTW-RW-MLGVAGVPAIVQF-VLMLSLPESPRWLYR 216

  Fly   214 RGQEERARKALKWL-RGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKP-----LSIS 272
            :.:...:|..|:.: ...|.:.|.|..:|......||.....::.....|.....|     |:..
plant   217 KDRIAESRAILERIYPADEVEAEMEALKLSVEAEKADEAIIGDSFSAKLKGAFGNPVVRRGLAAG 281

  Fly   273 LGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSN---LSTIIVGVVNFFATFMGIILIDRLGRKIL 334
            :.:...|||.|||.|::|:..|.:.||...:..   ||.|..| :|...:.:.::.:||.||:.|
plant   282 ITVQVAQQFVGINTVMYYSPSIVQFAGYASNKTAMALSLITSG-LNALGSIVSMMFVDRYGRRKL 345

  Fly   335 LYVSDIAMIVTLSILGGFF----------------------YCKAHGP----------------- 360
            :.:|...:|..|.||...|                      .|.|:.|
plant   346 MIISMFGIIACLIILATVFSQAAIHAPKIDAFESRTFAPNATCSAYAPLAAENAPPSRWNCMKCL 410

  Fly   361 ------------------------DV-----------------SHLGWLPLTCFVIYILGFSLGF 384
                                    |:                 |..|:|.:....:||:.::.|.
plant   411 RSECGFCASGVQPYAPGACVVLSDDMKATCSSRGRTFFKDGCPSKFGFLAIVFLGLYIVVYAPGM 475

  Fly   385 GPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFF 449
            |.:||::..||.|.:.||....:....||....:|:::|..||.|:|:.|.|.||.....:||||
plant   476 GTVPWIVNSEIYPLRYRGLGGGIAAVSNWVSNLIVSESFLSLTHALGSSGTFLLFAGFSTIGLFF 540

  Fly   450 VIIFVPETRGKSLEEIERKMMGRVPMSSVVNIKP 483
            :.:.||||:|...||:|:.:        .|..||
plant   541 IWLLVPETKGLQFEEVEKLL--------EVGFKP 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	140/536 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	132/522 (25%)
INT4	NP_001328028.1	MFS_HMIT_like	33..547	CDD:340918	132/523 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810