DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT3G20460

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_188681.1	Gene:	AT3G20460 / 821591	AraportID:	AT3G20460	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	440	Identity:	127/440 - (28%)
Similarity:	230/440 - (52%)	Gaps:	25/440 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SLC-SLVVGFVSAYTSPA---LVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYL 96
            :|| :...|..:.:||||   :::..:.::..|       |:.|.::.:..|.|....|.|.:..
plant    60 ALCGTFSYGTAAGFTSPAQTGIMAGLNLSLAEF-------SFFGAVLTIGGLVGAAMSGKLADVF 117

  Fly    97 GRRSTILATAVPFIVSS-LLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLG 160
            |||.. |..:..|.::. |:||.:.....:..||...|...|:||..:|||:.|....:||||..
plant   118 GRRGA-LGVSNSFCMAGWLMIAFSQATWSLDIGRLFLGVAAGVASYVVPVYIVEIAPKKVRGTFS 181

  Fly   161 LLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPF-LILMIIIPETPRWFVNRGQEERARKAL 224
            .:.:.:....:.|.|:.||.::|..||.: :.:|..| .:.:..|||:|||....|:.:.:..:|
plant   182 AINSLVMCASVAVTYLLGSVISWQKLALI-STVPCVFEFVGLFFIPESPRWLSRNGRVKESEVSL 245

  Fly   225 KWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIF 289
            :.|||...|:..|..|: :...|..::..::...:||.....:.:::.:||:..||..|::...|
plant   246 QRLRGNNTDITKEAAEI-KKYMDNLQEFKEDGFFDLFNPRYSRVVTVGIGLLVLQQLGGLSGYTF 309

  Fly   290 YTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFY 354
            |...|||.:|  ..:|:..::..||....:.:||:::|:.||:.||.|:.|.|.:...|.|..|.
plant   310 YLSSIFKKSG--FPNNVGVMMASVVQSVTSVLGIVIVDKYGRRSLLTVATIMMCLGSLITGLSFL 372

  Fly   355 CKAHGPDVSHLGWLPLTCF---VIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCT 416
            .:::|. :.|  :.|::.|   ::::...::|.|.|||:|:.|:.|..|:|.|.::....:|...
plant   373 FQSYGL-LEH--YTPISTFMGVLVFLTSITIGIGGIPWVMISEMTPINIKGSAGTLCNLTSWSSN 434

  Fly   417 FVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIE 466
            :.|:.||..| ....:.|.|:::..|..||:.||:..||||||:|||||:
plant   435 WFVSYTFNFL-FQWSSSGVFFIYTMISGVGILFVMKMVPETRGRSLEEIQ 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	127/440 (29%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	116/426 (27%)
AT3G20460	NP_188681.1	MFS_GLUT6_8_Class3_like	54..481	CDD:340916	124/436 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.920