DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT3G05400

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_187191.2	Gene:	AT3G05400 / 819704	AraportID:	AT3G05400	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	135/454 - (29%)
Similarity:	221/454 - (48%)	Gaps:	38/454 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALA 84
            :.|:|||            ...:|: :|.|..:::|..|.::..|       |..|.:.....:.
plant    34 VSASFTF------------GAAIGY-TADTMSSIMSDLDLSLAQF-------SLFGSLSTFGGMI 78

  Fly    85 GGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGE 149
            |.|.........|.:.|:....:..|...|.|:.|.::|.:..||||.|..||:.|..:|||:.|
plant    79 GAIFSAKAASAFGHKMTLWVADLFCITGWLAISLAKDIIWLDMGRFLVGIGVGLISYVVPVYIAE 143

  Fly   150 TLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMI---IIPETPRWF 211
            .....|||........|.|.|:.|.|..|:|::|..||.:|:   :|..|.:|   .|||:|||.
plant   144 ITPKHVRGAFTFSNQLLQNCGVAVVYYFGNFLSWRTLAIIGS---IPCWIQVIGLFFIPESPRWL 205

  Fly   212 VNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLM 276
            ..:|:::...:.|:.|||::.|:.||..|:..| .:|.::.:......||::.....|:|.:|||
plant   206 AKKGRDKECEEVLQKLRGRKYDIVPEACEIKIS-VEASKKNSNINIRSLFEKRYAHQLTIGIGLM 269

  Fly   277 FFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIA 341
            ..||..|...:..|...:||.||  ..:.:..:::.::....:.||:||:||.||:.||..|.:.
plant   270 LLQQLCGTAGISSYGSTLFKLAG--FPARIGMMVLSLIVVPKSLMGLILVDRWGRRPLLMTSALG 332

  Fly   342 MIVTLSILGGFFYCKAHGPDVSHLGWL-PLTCFV---IYILGFSLGFGPIPWLMMGEILPAKIRG 402
            :.::...|...|..|    ||..:|.: |:.||:   .:.:.|::|.|.:||::|.||.|..|:.
plant   333 LCLSCITLAVAFGVK----DVPGIGKITPIFCFIGILSFTMMFAIGMGALPWIIMSEIFPMDIKV 393

  Fly   403 PAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIE 466
            .|.|:||..|||..::....|..:.| ....|.|.:...||...:.|....|||||..:||||:
plant   394 LAGSLVTIANWFTGWIANYAFNFMLV-WSPSGTFIISAIICGATIVFTWCLVPETRRLTLEEIQ 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	131/443 (30%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	122/427 (29%)
AT3G05400	NP_187191.2	Sugar_tr	30..459	CDD:278511	135/454 (30%)
AT3G05400	NP_187191.2	MFS	30..444	CDD:119392	126/440 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930