DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT3G05160

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_566247.1	Gene:	AT3G05160 / 819679	AraportID:	AT3G05160	Length:	458	Species:	Arabidopsis thaliana

Alignment Length:	454	Identity:	144/454 - (31%)
Similarity:	229/454 - (50%)	Gaps:	29/454 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VLAALSVSLC-SLVVGFVSAYTS---PALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITG 89
            |:.:..|::| |...|..:.|||   .|::...|.::..|       |..|..:.|....|.:..
plant    21 VILSTFVAVCSSFSYGCANGYTSGAETAIMKELDLSMAQF-------SAFGSFLNLGGAVGALFS 78

  Fly    90 GPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPE 154
            |.|...||||.|:.|..:..|...|.||.|.||:.:..||...|..||:.|..:|||:.|.....
plant    79 GQLAVILGRRRTLWACDLFCIFGWLSIAFAKNVLWLDLGRISLGIGVGLTSYVVPVYIAEITPKH 143

  Fly   155 VRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALP--VPFLILMIIIPETPRWFVNRGQE 217
            |||........|.|.||.:.|..|:.:||.:||.:| |||  :| :|.:..|||:|||....|..
plant   144 VRGAFSASTLLLQNSGISLIYFFGTVINWRVLAVIG-ALPCFIP-VIGIYFIPESPRWLAKIGSV 206

  Fly   218 ERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFS 282
            :....:|..||||:|||..|..|:.......:..:..:.| ::|::...:.|.:.:|||..||.|
plant   207 KEVENSLHRLRGKDADVSDEAAEIQVMTKMLEEDSKSSFC-DMFQKKYRRTLVVGIGLMLIQQLS 270

  Fly   283 GINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLS 347
            |.:.:.:|:..||:.||  ....|.::|.||.......:|:||:||.||:.||..|.:.|.:...
plant   271 GASGITYYSNAIFRKAG--FSERLGSMIFGVFVIPKALVGLILVDRWGRRPLLLASAVGMSIGSL 333

  Fly   348 ILGGFFYCKAHG--PDVSHLGWLPLTCFV---IYILGFSLGFGPIPWLMMGEILPAKIRGPAASV 407
            ::|..|..:...  |:     ::|:..|:   :|...|::|.|.:||::|.||.|..|:..|.|:
plant   334 LIGVSFTLQEMNLFPE-----FIPVFVFINILVYFGFFAIGIGGLPWIIMSEIFPINIKVSAGSI 393

  Fly   408 VTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMG 471
            |...:|...:.|:..| :......|.|.|::|..:..:.|.|:.:.||||:|:||||::..:.|
plant   394 VALTSWTTGWFVSYGF-NFMFEWSAQGTFYIFAMVGGLSLLFIWMLVPETKGQSLEELQASLTG 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	142/446 (32%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	133/431 (31%)
AT3G05160	NP_566247.1	MFS_GLUT6_8_Class3_like	22..449	CDD:340916	140/444 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	292	1.000	Domainoid score	I356
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I822
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm972
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.930