DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and INT1

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_850393.1	Gene:	INT1 / 818934	AraportID:	AT2G43330	Length:	509	Species:	Arabidopsis thaliana

Alignment Length:	467	Identity:	147/467 - (31%)
Similarity:	232/467 - (49%)	Gaps:	38/467 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FTFSQVLA-ALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLA---ALA 84
            |..|.:|. .::..:..|:.|:.:...|.||:.:.|    .|||.|.:......|:.:|   |:.
plant    26 FGNSYILGLTVTAGIGGLLFGYDTGVISGALLYIKD----DFEVVKQSSFLQETIVSMALVGAMI 86

  Fly    85 GGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGE 149
            |...||.:.:|.||:...|...|.|...::::|.|.:..:::.||.|.|..||:||::.|||:.|
plant    87 GAAAGGWINDYYGRKKATLFADVVFAAGAIVMAAAPDPYVLISGRLLVGLGVGVASVTAPVYIAE 151

  Fly   150 TLQPEVRGTLGLLPTALGNI--GILVCYVAGSFM-----NWS-MLAFLGAALPVPFLILMIIIPE 206
            ....||||  ||:.|.:..|  |..:.|:..|..     .|. ||...|....:.| |||:.:||
plant   152 ASPSEVRG--GLVSTNVLMITGGQFLSYLVNSAFTQVPGTWRWMLGVSGVPAVIQF-ILMLFMPE 213

  Fly   207 TPRWFVNRGQEERARKALKWLRGKEADV---EPELKELMQSQADADRQATQNTC--LELFKRNNL 266
            :|||...:.::..|.:.|    .:..|:   |.|:..|  |.|:.:.:..:.|.  |::|:...|
plant   214 SPRWLFMKNRKAEAIQVL----ARTYDISRLEDEIDHL--SAAEEEEKQRKRTVGYLDVFRSKEL 272

  Fly   267 KPLSIS-LGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSN----LSTIIVGVVNFFATFMGIILI 326
            :...:: .||..||||:|||.|::|:..|.:.||  ..||    ..::||..:|...|.:||..|
plant   273 RLAFLAGAGLQAFQQFTGINTVMYYSPTIVQMAG--FHSNQLALFLSLIVAAMNAAGTVVGIYFI 335

  Fly   327 DRLGRKILLYVSDIAMIVTLSILG-GFFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWL 390
            |..|||.|...|...:|::|.||. .||.......|....|||.:....:||:.|:.|.||:||.
plant   336 DHCGRKKLALSSLFGVIISLLILSVSFFKQSETSSDGGLYGWLAVLGLALYIVFFAPGMGPVPWT 400

  Fly   391 MMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVP 455
            :..||.|.:.||....:....||....:|.:||..:..|.|....|.:...|.::.:.|||:|||
plant   401 VNSEIYPQQYRGICGGMSATVNWISNLIVAQTFLTIAEAAGTGMTFLILAGIAVLAVIFVIVFVP 465

  Fly   456 ETRGKSLEEIER 467
            ||:|.:..|:|:
plant   466 ETQGLTFSEVEQ 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	143/458 (31%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	136/442 (31%)
INT1	NP_850393.1	Sugar_tr	34..479	CDD:278511	144/459 (31%)
INT1	NP_850393.1	MFS	35..464	CDD:119392	136/443 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810