DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and INT3

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_181117.1	Gene:	INT3 / 818146	AraportID:	AT2G35740	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	147/557 - (26%)
Similarity:	239/557 - (42%)	Gaps:	142/557 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ALSVSLCSLVVGFVSAYTSPALVSMTDRTITSF-EVTKDAGSWVGGIMPLAALAGGIT----GGP 91
            |||..:..|:.|:.:...:.||:.:.:    .| ||  |..:|:..|:....:||.|.    ||.
plant    30 ALSAGIGGLLFGYNTGVIAGALLYIKE----EFGEV--DNKTWLQEIIVSMTVAGAIVGAAIGGW 88

  Fly    92 LIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVR 156
            ..:..|||.::|...|.|::.:|::..|....:|:.||.|.||.||:||::.|:|:.|.....:|
plant    89 YNDKFGRRMSVLIADVLFLLGALVMVIAHAPWVIILGRLLVGFGVGMASMTSPLYISEMSPARIR 153

  Fly   157 GTLGLLPTALGNIGILVCYVAGSFMNWSM-LAF----------LGAALPVPFLI---LMIIIPET 207
            |.|      :...|:|:  ..|.|:::.: |||          ||.: .:|.:|   ||:.:||:
plant   154 GAL------VSTNGLLI--TGGQFLSYLINLAFVHTPGTWRWMLGVS-AIPAIIQFCLMLTLPES 209

  Fly   208 PRWFVNRGQEERARKALKWLRGKEADVEPELKELMQS----QADAD----------RQATQNTCL 258
            |||.....::..:|..|:.:...|. ||.|:..|.:|    .||.|          |.|..|..:
plant   210 PRWLYRNDRKAESRDILERIYPAEM-VEAEIAALKESVRAETADEDIIGHTFSDKLRGALSNPVV 273

  Fly   259 ELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVV----NFFAT 319
            .       ..|:..:.:...|||.|||.|::|:..|.:.||..  ||.:.:.:.::    |...:
plant   274 R-------HGLAAGITVQVAQQFVGINTVMYYSPTILQFAGYA--SNKTAMALALITSGLNAVGS 329

  Fly   320 FMGIILIDRLGRKILLYVSDIAMIVTLSILGGFF----------------------YCKAHGP-- 360
            .:.::.:||.||:.|:.:|...:|..|.||...|                      .|.|..|
plant   330 VVSMMFVDRYGRRKLMIISMFGIITCLVILAAVFNEASNHAPKIDKRDSRNFAKNATCPAFAPFT 394

  Fly   361 ---------------------------------------DV-----------------SHLGWLP 369
                                                   |:                 |..|:|.
plant   395 ASRSPPSNWNCMKCLQYDCGFCSNGAQEYAPGACIVQSADMKALCHSKGRTFFKDGCPSKFGYLA 459

  Fly   370 LTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHG 434
            :....:||:.::.|.|.:||::..||.|.:.||.|..:....||....||::||..||.|:|:.|
plant   460 IVFLGLYIIVYAPGMGTVPWIVNSEIYPLRYRGLAGGIAAVSNWMSNLVVSETFLTLTNAVGSSG 524

  Fly   435 AFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMG 471
            .|.||.....|||||:.:.||||:|...||:|:.:.|
plant   525 TFLLFAGSSAVGLFFIWLLVPETKGLQFEEVEKLLEG 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	145/551 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	137/537 (26%)
INT3	NP_181117.1	SP	1..555	CDD:273317	144/549 (26%)
INT3	NP_181117.1	MFS	31..>364	CDD:119392	98/357 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810