DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT2G20780

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_179671.2	Gene:	AT2G20780 / 816607	AraportID:	AT2G20780	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	476	Identity:	143/476 - (30%)
Similarity:	240/476 - (50%)	Gaps:	53/476 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TFSQVLA-ALSVSLCSLVVGF-VSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGI 87
            |...|:| |...||.::::|: |...:...|....|..||..:.....||     :.:.:|.|.:
plant    51 TRKYVMACAFFASLNNVLLGYDVGVMSGAVLFIQQDLKITEVQTEVLIGS-----LSIISLFGSL 110

  Fly    88 TGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQ 152
            .||...:.:||:.|:...|:.|...:.::|.|.:..:::.||.|.|..:|:..:..|||:.|...
plant   111 AGGRTSDSIGRKWTMALAALVFQTGAAVMAVAPSFEVLMIGRTLAGIGIGLGVMIAPVYIAEISP 175

  Fly   153 PEVRGTLGLLPTALGNIGILVCYVAG-SF------MNWSMLAFLGAALPVPFL-ILMIIIPETPR 209
            ...||.....|....|:|||:.||:. :|      ::|.::..:| .||..|: ..:.:|||:||
plant   176 TVARGFFTSFPEIFINLGILLGYVSNYAFSGLSVHISWRIMLAVG-ILPSVFIGFALCVIPESPR 239

  Fly   210 WFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNL--KPLSIS 272
            |.|.:|:.:.||:.|.....::.:.|..|.|:..:.|..:....:....||...:.:  |.|.:.
plant   240 WLVMKGRVDSAREVLMKTNERDDEAEERLAEIQLAAAHTEGSEDRPVWRELLSPSPVVRKMLIVG 304

  Fly   273 LGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNL--STIIVGVVN----FFATFMGIILIDRLGR 331
            .|:..|||.:||:|.::|:.:|.|:||...::.|  :|:.|||..    .||||    |||.:||
plant   305 FGIQCFQQITGIDATVYYSPEILKEAGIQDETKLLAATVAVGVTKTVFILFATF----LIDSVGR 365

  Fly   332 KILLYVSDIAMIV-------TLSILGGFFYCKAHGPDVSHLGWLPLTCFVIYILG----FSLGFG 385
            |.|||||.|.|.:       ||:.||              .|.|.:|..::::.|    ||:|.|
plant   366 KPLLYVSTIGMTLCLFCLSFTLTFLG--------------QGTLGITLALLFVCGNVAFFSIGMG 416

  Fly   386 PIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFV 450
            |:.|::..||.|.::|..|:::....|..|:.:|..:|..::.|:...|.|::|..:..:.:.||
plant   417 PVCWVLTSEIFPLRLRAQASALGAVGNRVCSGLVAMSFLSVSRAITVGGTFFVFSLVSALSVIFV 481

  Fly   451 IIFVPETRGKSLEEIERKMMG 471
            .:.||||.|||||:||....|
plant   482 YVLVPETSGKSLEQIELMFQG 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	139/464 (30%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	127/448 (28%)
AT2G20780	NP_179671.2	MFS_PLT	61..496	CDD:340995	136/458 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810