DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and AT2G18480

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_179438.1	Gene:	AT2G18480 / 816363	AraportID:	AT2G18480	Length:	508	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	153/514 - (29%)
Similarity:	245/514 - (47%)	Gaps:	69/514 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LMRADTHVSF--SVPADGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDR---TITS 63
            ::.||.| :|  |.|...:. .|.|.   .|:..|:.|::.|:.:...|.|.:.:.|.   ..|.
plant     1 MVHADGH-NFPGSDPNPHMN-KFAFG---CAIVASIISIIFGYDTGVMSGAQIFIRDDLKINDTQ 60

  Fly    64 FEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCG 128
            .||       :.||:.|.||.|.:|.|...:.:|||.||..:||.|:|.|:|:....|..:::.|
plant    61 IEV-------LAGILNLCALVGSLTAGKTSDVIGRRYTIALSAVIFLVGSVLMGYGPNYPVLMVG 118

  Fly   129 RFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVA----GSF---MNWSML 186
            |.:.|..||.|.:..|||..|......||.|..||....::|||:.||:    |..   :.|.::
plant   119 RCIAGVGVGFALMIAPVYSAEISSASHRGFLTSLPELCISLGILLGYVSNYCFGKLTLKLGWRLM 183

  Fly   187 AFLGAALPVPFLILMIII---PETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADA 248
              ||.| ..|.|||...|   ||:|||.|.:|:.|.|:|.:..:...|.:.|...:::: :.|:.
plant   184 --LGIA-AFPSLILAFGITRMPESPRWLVMQGRLEEAKKIMVLVSNTEEEAEERFRDIL-TAAEV 244

  Fly   249 DRQATQNTCLELFKRNN---------LKP-------LSISLGLMFFQQFSGINAVIFYTVQIFKD 297
            |....:.....:.|:|:         :||       |..::|:.||:..:||.||:.|:.:|||.
plant   245 DVTEIKEVGGGVKKKNHGKSVWRELVIKPRPAVRLILIAAVGIHFFEHATGIEAVVLYSPRIFKK 309

  Fly   298 AGSTIDSN--LSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMI-------VTLSILGGFF 353
            ||......  |:|:.||:...|...:...|:|::||:.||..|...|:       |:|:::..|
plant   310 AGVVSKDKLLLATVGVGLTKAFFIIIATFLLDKVGRRKLLLTSTGGMVFALTSLAVSLTMVQRF- 373

  Fly   354 YCKAHGPDVSHLGW---LPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFC 415
                     ..|.|   |.:.....::..||:|.|||.|:...||.|.::|...||:..|.|...
plant   374 ---------GRLAWALSLSIVSTYAFVAFFSIGLGPITWVYSSEIFPLRLRAQGASIGVAVNRIM 429

  Fly   416 TFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVP 474
            ...|:.:|..:|.|:...|.|::|..|.:...:|....:|||:|..|||:|:...|..|
plant   430 NATVSMSFLSMTKAITTGGVFFVFAGIAVAAWWFFFFMLPETKGLPLEEMEKLFGGGGP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	142/476 (30%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	134/461 (29%)
AT2G18480	NP_179438.1	MFS_PLT	36..479	CDD:340995	138/463 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820