Protein Alignment Tret1-2 and SLC2A10

DIOPT Version :9

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 143/542 - (26%)
• Similarity: 229/542 - (42%)
• Gaps: 131/542 - (24%)

  Fly    20 LKANFTFSQVLAALSVSLCSLVVGF-VSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAAL 83
            |....||...||.:|.:|..|.:.| :|......||                     |.:.|.||
Human    37 LLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLV---------------------GSLLLGAL 80

  Fly    84 AGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLG 148
            ...:.||.||:..||:..||.:.:..:..||.:..|.::..::.||.:.||.:.::|::..:|:.
Human    81 LASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVS 145

  Fly   149 ETLQPEVRGTLGLLPTALGNIGILVCY-----VAGSFMNWSMLAFLGAALPVPFLILMIIIPETP 208
            |.:.|..||.|..|..|...:|||:.|     :||:...|..: |..|..|.....|.::
Human   146 ELVGPRQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHM-FGWATAPAVLQSLSLL----- 204

  Fly   209 RWFVNRGQEERA-RKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFK-RNNLK-PLS 270
              |:..|.:|.| .|.|..|:|.||   |:|          .....:.:.|:||: |:|:: ..:
Human   205 --FLPAGTDETATHKDLIPLQGGEA---PKL----------GPGRPRYSFLDLFRARDNMRGRTT 254

  Fly   271 ISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSN--LSTIIVGVVNFFATFMGIILIDRLGRKI 333
            :.|||:.|||.:|...|:.|...||...|....|:  |:::.:|.|...||...:.|:||.||:.
Human   255 VGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRA 319

  Fly   334 LLYVSDIAMIVTLSILGGFFYC------------------------------------------- 355
            ||......|.:::|.:|...:.
Human   320 LLLAGCALMALSVSGIGLVSFAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQ 384

  Fly   356 -----------KAH-------------------GPDVSHLG-----WLPLTCFVIYILGFSLGFG 385
                       |.|                   ||.:...|     |..|.|.::::..||.|||
Human   385 REPILSTAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFG 449

  Fly   386 PIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFV 450
            |:.||::.||.|.:|||.|.:...:|||.....::.:|.||...:|....|.|:|...::||.|:
Human   450 PVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFI 514

  Fly   451 IIFVPETRGKSLEEIERKMMGR 472
            .:|||||:|:||.||:::...|
Human   515 YLFVPETKGQSLAEIDQQFQKR 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	138/524 (26%)
		MFS	33..454	CDD:119392	127/509 (25%)
SLC2A10	XP_011527362.1	Sugar_tr	32..533	CDD:278511	142/537 (26%)
		MFS	35..518	CDD:119392	132/522 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144161
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750