DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a1

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001072458.1	Gene:	slc2a1 / 779913	XenbaseID:	XB-GENE-5755357	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	483	Identity:	135/483 - (27%)
Similarity:	235/483 - (48%)	Gaps:	71/483 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QVLAALSVSLCSLVVG-------------------------FVSAYTSPALVSMTDRTITSFEVT 67
            ::.|.|.:::|:.|:|                         ::..|..|    :.:.|:||....
Frog     6 KMTARLMLAVCTAVIGSLQFGYNTGVINAPQEVIEGFYNATWLERYNEP----IPESTLTSLWSL 66

  Fly    68 KDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIA---CAVNVIMILCGR 129
            ..|...|||      :.|..:.|..:...|||:::|...|...::::|:.   .||:..|::.||
Frog    67 SVAIFSVGG------MVGSFSVGLFVNRFGRRNSMLMANVLAFLAAILMGFSKLAVSFEMLIIGR 125

  Fly   130 FLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAG---SFMNWSMLAFLGA 191
            |:.|...|:.:..:|:|:||.....:||.||.|......:|||:..:.|   ...|.|:..||..
Frog   126 FVVGLYCGLTTGFVPMYVGEVSPTSLRGALGTLHQLGVVVGILIAQIFGLKPIMGNDSLWPFLLG 190

  Fly   192 ALPVPFLILMIII---PETPRW-FVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQA 252
            .:.:|.::..|::   ||:||: .:||.:|::|:..||.||| ..||..:|:|:.:......|:
Frog   191 CIFIPAILQCIMLPFCPESPRFLLINRNEEDKAKSVLKKLRG-TTDVSSDLQEMKEESRQMMRE- 253

  Fly   253 TQNTCLELFKRNNL--KPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNL-STIIVGVV 314
            .:.|.|||| |:.|  :|:.|::.|...||.||||||.:|:..||:.|  .::..: :||..|:|
Frog   254 KKVTILELF-RSPLYRQPMFIAIILQLSQQLSGINAVFYYSTMIFQKA--QVEQPVYATIGAGIV 315

  Fly   315 NFFATFMGIILIDRLGRKIL-------LYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTC 372
            |...|.:.:.:::|.||:.|       :.|..|.|.:.|::|          ..|..:.:|.:..
Frog   316 NTAFTVVSLFVVERAGRRTLHLIGLGGMAVCAILMTIALALL----------DSVGGMSYLSIVA 370

  Fly   373 FVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFW 437
            ...::..|.:|.|||||.::.|:.....|..|.:|....||...|:|...||.:....||: .|.
Frog   371 IFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGLSNWTSNFIVGMGFQYVEQLCGAY-VFI 434

  Fly   438 LFGAICIVGLFFVIIFVPETRGKSLEEI 465
            :|..:.::...|....||||:|::.:||
Frog   435 IFTVLLLIFFVFTYFKVPETKGRTFDEI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	135/480 (28%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	127/465 (27%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	130/469 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000