Protein Alignment Tret1-2 and SLC2A11

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_001269793.1
• Gene: SLC2A11 / 66035
• HGNCID: 14239
• Length: 535
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 108/477 - (22%)
• Similarity: 181/477 - (37%)
• Gaps: 104/477 - (21%)

  Fly    14 SVPADGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIM 78
            ::.|.|:...|.|     ..::|:.:.....:..:|:....:.|...:....|.. ..|.:..:.
Human    23 TICAAGIGGTFQF-----GYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLL-MWSLIVSLY 81

  Fly    79 PLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLI----ACAVNVIMILCGRFLTGFCVGIA 139
            ||..|.|.:..|||...|||:.::|...: |:||:.::    ..|.:..||:.||.|.|...|::
Human    82 PLGGLFGALLAGPLAITLGRKKSLLVNNI-FVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVS 145

  Fly   140 SLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLIL---- 200
            ....|:||||:...|:||.:.:.......:||::..|.|      :...||.....|.|:.
Human   146 MNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVG------LRELLGGPQAWPLLLASCLV 204

  Fly   201 --------MIIIPETPRW-FVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNT 256
                    :.::||:||: .::.|..|....||:.||| ..|:..||:||     :.:|.|.|.
Human   205 PGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRG-SGDLAGELEEL-----EEERAACQG- 262

  Fly   257 C-----LELFKRNNLKPLSISLGLM-FFQQFSGINAVIFYTVQIFKDAG-----------STIDS 304
            |     .|||:...|:....||.:: ...:..|.::|..|...:|:.||           .|...
Human   263 CRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSC 327

  Fly   305 NLSTIIV---GVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLG 366
            .|.|.:|   ||...:....|:.......|                            |..|...
Human   328 ELLTAVVSVAGVDEGWGVQAGLTSTSPPPR----------------------------PRQSSFP 364

  Fly   367 W---LPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTV 428
            |   |.:.|...:||.|.:|...:..::..|:.....|..|..|..|..|...         :.|
Human   365 WTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIML---------ILV 420

  Fly   429 AMGAHGAFWLFGAICIVGLFFV 450
            .:|       |..|.::|.|.:
Human   421 GLG-------FPFIMVLGSFLI 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	104/462 (23%)
SLC2A11	NP_001269793.1	MFS	23..433	CDD:475125	107/473 (23%)