DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a9l1

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001159589.1	Gene:	slc2a9l1 / 565510	ZFINID:	ZDB-GENE-090915-3	Length:	491	Species:	Danio rerio

Alignment Length:	474	Identity:	122/474 - (25%)
Similarity:	228/474 - (48%)	Gaps:	66/474 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LVVGFVSAYTSP-ALVSMTDRT--ITSF----------EVTKDAG---SWVGGIMPLAALAGGIT 88
            :|:||..::.:. .|.|::..|  |.||          .:.|::.   .| ..::.|..| ||:.
Zfish    18 IVLGFGGSFQNGFHLTSISSPTPYIQSFINSSWTHHYGHIPKESTITFIW-SAVVALYGL-GGLI 80

  Fly    89 GGPLIEYLGR-----RSTILATAVPFIVSSLLIAC--AVNVIMILCGRFLTGFCVGIASLSLPVY 146
            |...::||.|     |:|:|.:|:..:.|.::...  ..:..:||..|||.||..|:......:|
Zfish    81 GSSSVKYLTRRLGRKRTTLLNSAIAVVASIIMYISKPTYSFELILIARFLFGFIAGLGLNVHSIY 145

  Fly   147 LGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMN----------WSMLAFLGAALPVPFLILM 201
            |||:...::||.: ||.:|   |.:.:..::|.|..          |::|....:...|..|.::
Zfish   146 LGESSPKKIRGVV-LLTSA---IFLALGKLSGQFAGLREILGREEWWNILLCFPSVFCVIQLAVL 206

  Fly   202 IIIPETPRW-FVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQN-TCLELFKRN 264
            ..:|:.||: .:.:...|:.||||::|.|. .:.:.|::|:.:.||....:  || :.|:|.:..
Zfish   207 PFLPDAPRYILIEKNNTEQCRKALQYLWGL-GEYKMEIEEMSEEQAVIGEK--QNMSVLDLLRDK 268

  Fly   265 NLK-----PLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDS-NLSTIIVGVVNFFATFMGI 323
            :::     .|.:::|:    |||||:|:..::..||.:||...|. ...|:.:|......|....
Zfish   269 SVRWQVISLLVLNIGI----QFSGISAITIFSFNIFLEAGIPEDKIRYVTLGIGASEVLITITCG 329

  Fly   324 ILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLP-LTCFVIYILGFSLGFGPI 387
            :.|:|:|||.|::.....|.|.::::....|.:    |.|.:  :| .|.|:|::.....|.||.
Zfish   330 LFIERVGRKPLMWRGFGGMSVVMALIIVTLYLR----DYSFV--IPYFTVFLIFLFMIFYGGGPA 388

  Fly   388 PWL--MMGEILPAKIRGPAASV-VTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFF 449
            ..:  :..|:.....| |||.| :....|....::...|..|.|.:.:. :|.||..||::...:
Zfish   389 ATVGAVCNEMFIQSYR-PAAFVYIGILRWVGFTLLGFVFPFLIVVLKSL-SFVLFSCICLLAALY 451

  Fly   450 VIIFVPETRGKSLEEIERK 468
            :...:|||:||::.||.::
Zfish   452 IFFILPETKGKTILEISQE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	122/471 (26%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	115/458 (25%)
slc2a9l1	NP_001159589.1	Sugar_tr	14..471	CDD:278511	122/474 (26%)
slc2a9l1	NP_001159589.1	MFS	18..455	CDD:119392	115/457 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576999
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850