DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	496	Identity:	138/496 - (27%)
Similarity:	220/496 - (44%)	Gaps:	93/496 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 CSLVV-GFVSAYTSP-------ALVSMTDRTITSF-----------EVTKDAGSWVGGIMPLAAL 83
            |||:| ..|.|:.|.       ::|:.....|.:|           .:..|..:.:..:......
  Rat    42 CSLIVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPIDPDTLTLLWSVTVSIFA 106

  Fly    84 AGGITGGPLI----EYLGRRSTILATAVPFIVSSLLIACAVNV---IMILCGRFLTGFCVGIASL 141
            .||:.|..::    ::|||:.|:|......|.::||:||::..   .|::.|||:.|...|||..
  Rat   107 IGGLVGTLMVKMIGKFLGRKYTLLVNNGFAISAALLMACSLQAGTFEMLIVGRFIMGVDGGIALS 171

  Fly   142 SLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIII-- 204
            :||:||.|....|:||:||.: ||     |.:|....|.....:...||.....|:|..:||:
  Rat   172 ALPMYLNEISPKEIRGSLGQV-TA-----IFICIGVFSGQLLGLPELLGKERTWPYLFGVIIVPA 230

  Fly   205 ----------PETPRWFV-NRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCL 258
                      ||:||:.: .:..|..|.||.:...|| |||..||:|.: :::...|.....:..
  Rat   231 LAQLASLPFLPESPRYLLFEKHDEAGATKAFQTFLGK-ADVSQELEEAL-AESRVQRNLRLVSVF 293

  Fly   259 ELFKRNNLKPLSISLGL-MFFQQFSGINAVIFYTVQIFKDAGSTIDS----NLSTIIVGVVNFFA 318
            ||.:...::...|::.: |...|..|:||:.|||..||..||...|.    .|||  .|:....|
  Rat   294 ELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIFGKAGVPQDKIPYITLST--GGIETLAA 356

  Fly   319 TFMGIILIDRLGRKILLYVSDIAMIVTLSILGGF-----FY--------CKAHGPDVSHLGWLP- 369
            .|.|:: |:||||:.||             :|||     |:        .:...|      |:|
  Rat   357 IFSGLV-IERLGRRPLL-------------IGGFGLMALFFGMLTVTLTLQDQAP------WIPY 401

  Fly   370 --LTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVT-AFNWFCTFVVTKTFQDLTVAMG 431
              :.|.:..|..|..|.|.||:::.||......| |||.::. ..||...|||...|..:..::.
  Rat   402 LSIVCILAIIASFCSGPGGIPFILTGEFFQQSER-PAAFIIAGTVNWLSNFVVGLLFPFIQKSLE 465

  Fly   432 AHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGR 472
            :: .|.:|..|||.|..:....:|||:.::..||.:....|
  Rat   466 SY-CFLVFATICIAGAIYFYFVLPETKNRTHAEISQAFAKR 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	137/489 (28%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	132/476 (28%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	133/486 (27%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	128/468 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840