DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and slc2a3a

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_005159482.1	Gene:	slc2a3a / 436916	ZFINID:	ZDB-GENE-040718-390	Length:	575	Species:	Danio rerio

Alignment Length:	515	Identity:	146/515 - (28%)
Similarity:	231/515 - (44%)	Gaps:	78/515 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSF---------------EVTKDAGSWVGGI 77
            ||...|..||.:.|:|.:....:..:::..::.:.:|               .|.....|:...|
Zfish     7 QVTCYLLFSLSTAVIGSLQFGYNTGVINAPEQKLRAFFNATWMERYGEPISPGVCTIVWSFAVAI 71

  Fly    78 MPLAALAGGITGGPLIEYLGRR-STILATAVPFIVSSLLIACAV--NVIMILCGRFLTGFCVGIA 139
            ..:..:||..:.|.:....||| |.||...:..|...|:..|.:  :..||:.||.:.|...|:.
Zfish    72 FSVGGMAGSFSVGVVANKFGRRKSMILVNVLALIGGGLMGLCTLCSSFEMIIAGRLMIGLFCGLF 136

  Fly   140 SLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIII 204
            :...|:|:||.....:||..|.|......:|||:..:.|      :.:.||:....|.|:.:.|:
Zfish   137 TGLTPMYVGEVSPTPLRGAFGTLHQLGVVVGILIAQIFG------LESLLGSDKLWPILLALTIL 195

  Fly   205 ------------PETPRW-FVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQN- 255
                        ||:||: .:|..:||:|||||..|||.| ||..:::|:.:..|   :.|.:.
Zfish   196 PAILQCFLLPFCPESPRYLLINLNEEEQARKALVRLRGYE-DVGKDMQEMKEESA---KMAMEKK 256

  Fly   256 -TCLELFKRNNLK-PLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFA 318
             |..|||:....: ||.|::.|...||.||||||.:|:..|||.||.| ....:||..||||...
Zfish   257 VTIPELFRSAAYRQPLFIAIMLQLSQQLSGINAVFYYSTGIFKSAGVT-QPIYATIGAGVVNTVF 320

  Fly   319 TFMGIILIDRLGRKIL-------LYVSDIAMIVTLSILGGFFYC--------------------- 355
            |.:.:.|::|.||:.|       :.:|.:||.:.| :|..|..|
Zfish   321 TVVSLFLVERAGRRTLHLIGLGGMAISALAMTIAL-LLVRFTVCFNFVKILNQPQQYLMIMVNVF 384

  Fly   356 ---KAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTF 417
               .:...|:..|.:|.:.....::..|.:|.|||||.::.|:.....|..|.:|....||...|
Zfish   385 ITFVSKQKDIEALQYLSIAAIFAFVAMFEMGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTANF 449

  Fly   418 VVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVPMSS 477
            :|..||..|....|.: .|.:|....|:...|....||||:|::.:||.|...|..|.|:
Zfish   450 IVGITFPKLEELCGPY-VFIIFMIFLIIFFIFTYFKVPETKGRTFDEIARGFSGAPPPSA 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	140/500 (28%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	133/485 (27%)
slc2a3a	XP_005159482.1	Sugar_tr	18..500	CDD:278511	138/494 (28%)
slc2a3a	XP_005159482.1	MFS	66..466	CDD:119392	122/412 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.740