Protein Alignment Tret1-2 and slc2a8

DIOPT Version :10

• Sequence 1: NP_610694.1
• Gene: Tret1-2 / 36249
• FlyBaseID: FBgn0033644
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_997963.1
• Gene: slc2a8 / 373140
• ZFINID: ZDB-GENE-030829-25
• Length: 498
• Species: Danio rerio
• Alignment Length: 467
• Identity: 166/467 - (35%)
• Similarity: 252/467 - (53%)
• Gaps: 32/467 - (6%)

  Fly    25 TFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITG 89
            ||:.||..||       .|||..|:|||:..:........:::.:..||.|.::.:.|..||:.|
Zfish    40 TFAAVLGPLS-------FGFVLGYSSPAIPELRRIQDLRLQLSVEEASWFGSVVTIGAALGGLLG 97

  Fly    90 GPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPE 154
            |.::|.:||:.:::..|:|||.....|..|.|..|...||.|||...|:.||.:|:|:.|.....
Zfish    98 GWIVERIGRKLSLMFCAIPFIFGFTTIIAAQNHWMFYVGRVLTGLASGVTSLVVPLYISEMAHER 162

  Fly   155 VRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEER 219
            ||||||.....:..|||:..||.|.|::|..||...:..|...|:.|..:|||||:.:.:|:...
Zfish   163 VRGTLGSCVQLMVVIGIMGAYVTGLFLDWRWLAVASSIPPTLMLLSMCFMPETPRFLLCQGKRRE 227

  Fly   220 ARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCL-ELFKRNNLKPLSISLGLMFFQQFSG 283
            |..||::|||.:|..|.|...:    .||.:...|:..| :|......|||.|.:.:|..|||:|
Zfish   228 AEDALRFLRGPDAPAEWECARI----EDAYKNEEQSFSLGDLKDPGVYKPLGIGVMMMLLQQFTG 288

  Fly   284 INAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSI 348
            |||::||...||:.|... .|:::|:||.......|.:..:::|:.|||:||.:|.:.|.|:.::
Zfish   289 INAIMFYAETIFEQAHFK-SSDVATVIVAATQVVFTAIAALIMDKAGRKVLLILSGVVMCVSEAV 352

  Fly   349 LGGFFYCKAHGPDVS-------------------HLGWLPLTCFVIYILGFSLGFGPIPWLMMGE 394
            .|.:|......|:.|                   .|.||.:.....:|.||::|:||.|||:|.|
Zfish   353 FGVYFKLTVMKPNNSSMTSVLTDTHGLLEDQPSADLAWLAVGSMGFFIAGFAIGWGPTPWLVMSE 417

  Fly   395 ILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRG 459
            |.|.::||..:::....||.|.|:||||||:|..|:.:.|.||:|.|:|...:.|...|||||:|
Zfish   418 IFPTRVRGLGSALCVLTNWTCAFIVTKTFQNLMDALSSAGTFWMFSALCASNVVFTAFFVPETKG 482

  Fly   460 KSLEEIERKMMG 471
            |:||||:....|
Zfish   483 KTLEEIQAGFKG 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	MFS_GLUT6_8_Class3_like	29..464	CDD:340916	160/454 (35%)
slc2a8	NP_997963.1	MFS_GLUT8_Class3	37..487	CDD:340991	162/458 (35%)