DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and CG32054

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_729588.1	Gene:	CG32054 / 326185	FlyBaseID:	FBgn0052054	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	99/506 - (19%)
Similarity:	181/506 - (35%)	Gaps:	131/506 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTK-DAGSW-VGGIMPLAALAGGITGGPLIEYL 96
            :|....|:  |||...:.|. |:..|.:..::.|: :..:| :|||:      |.:....||..:
  Fly   123 AVGAAGLI--FVSGGMNIAW-SIGFRGVLHYKTTEHNFAAWFIGGII------GAVISWFLINNV 178

  Fly    97 GRRSTILATAVPFIVSSLLIACAVNV-IMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLG 160
            .::..::.::...::..:|.....|. ...|...:|.|...|:.........||.....:|   |
  Fly   179 AKKYVLIFSSFLVMIGGILTTSTKNSGDATLAASYLDGIANGLVFAPFMALAGEVSVSYMR---G 240

  Fly   161 LLPTALGNIGILVCYVAGSFM------NWSMLAF----------LGAALPVPFLILMIIIP---- 205
            ::..::..    :|:..|.|:      .|:..|:          :...|.:.:..|.:||.
  Fly   241 MVSASIEQ----MCFGLGIFLQIIYTSTWNSTAYPSYNSFSAENMKGVLSIIYGFLALIIGSLLC 301

  Fly   206 -ETPRWFVNRGQEER-ARKALKWLRGKEADVEPE--LKELMQSQADADRQATQNTCLELFKRNNL 266
             |:|...:.:..:|: |..||:.|:      .|.  ..|..:..|:..:...||
  Fly   302 IESPVIMLAKNNDEQGAIDALRRLQ------RPYTLTNETFEQLAEHKKYLAQN----------- 349

  Fly   267 KPLSI--SLG--------LMFFQQFSGINA------VIFYTVQIFKDAGSTIDSNLSTII-VGVV 314
            |.||:  |:|        |:|.:   |:||      |:...|..|......:..::...| .||.
  Fly   350 KELSMGQSIGQALPTFIRLVFLR---GLNAMSISKFVMIGFVYSFASPYGYVSPSVGWFIGFGVC 411

  Fly   315 NFFATFMGIILIDRLGRK----ILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTCFVI 375
            .:...|:....::..|||    :.|.|..:...|.......|.|...:.               |
  Fly   412 RWMGNFIATFCMESCGRKKPTLLGLIVCSVMSFVVAGQFNIFTYNTGNN---------------I 461

  Fly   376 YILGFSLGFG-----PIPWLMMGEILPAKIRGPAAS-----------VVTAFNWFCTFVVTKTFQ 424
            .:|.|.|..|     ..|:|  .|..|.:::....|           |:|...|
  Fly   462 MLLVFELFAGIAFTATSPYL--SEAFPLEVKQHFISFTFIGEMLVFLVLTLIRW----------- 513

  Fly   425 DLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVPM 475
               .:.|....|::.|.:.:.|.||.::.:||||..:|.|.:.|....:.|
  Fly   514 ---SSSGGANYFYVMGGLYLFGFFFGLVCLPETRRTTLREAQDKFSKFISM 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	97/496 (20%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	91/483 (19%)
CG32054	NP_729588.1	Pro-rich	<7..101	CDD:291893
CG32054	NP_729588.1	MFS	157..539	CDD:119392	82/445 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444529
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740