DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tret1-2 and itr2

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_593320.1	Gene:	itr2 / 2541827	PomBaseID:	SPAC20G8.03	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	474	Identity:	128/474 - (27%)
Similarity:	219/474 - (46%)	Gaps:	59/474 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIM------------PLA 81
            ||:|:: .:..|:.|:.:...|.||..:              ||.:|.::            ..|
pombe    83 VLSAVA-GISGLLFGYDTGVISGALAVL--------------GSDLGHVLSSGQKELITSATSFA 132

  Fly    82 ALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVY 146
            ||....|.|.|.:::||:..:|.....|::.|:::|.:.||.|::.|||:.|:.:|:.||.:|:|
pombe   133 ALISATTSGWLADWVGRKRLLLCADAIFVIGSVIMAASRNVAMMVVGRFIVGYGIGLTSLIVPMY 197

  Fly   147 LGETLQPEVRGTLGLLPTALGNIGILVCYVAGS-----FMNWSMLAFLGAALPVPFLILMIIIPE 206
            :.|.....:||.|.::.......|.|:.|...:     ...|.::..:|||..:..||.:...||
pombe   198 ITELAPARLRGRLVIIYVVFITGGQLIAYSLNAAFEHVHQGWRIMFGIGAAPALGQLISLFWTPE 262

  Fly   207 TPRWFVNRGQEERARKALKWLRGKEADVEPELK--------ELMQSQADAD------RQATQNTC 257
            :||:.:.....|:..|.|       :.:.||.|        .|:|.....|      .|...::.
pombe   263 SPRYLLRHNHVEKVYKIL-------SRIHPEAKPAEIAYKVSLIQEGVKVDFPEGNKFQHFFHSL 320

  Fly   258 LELFK-RNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFM 321
            ..||. .:|.:.|.|...|.:||||||.||:.:::..||:..|.....::| |:||..||..|.:
pombe   321 KVLFTVPSNRRSLFIGCFLQWFQQFSGTNAIQYFSAIIFQSVGFKNSISVS-IVVGATNFVFTIV 384

  Fly   322 GIILIDRLGRKILLYVSDIAMIVTLSILG-GFFYCKAHGPDVSHLGW--LPLTCFVIYILGFSLG 383
            ..:.|||:||:.:|..:...||..|::.. .:.:..|.....::.||  :.|...:|::..::.|
pombe   385 AFMFIDRIGRRRILLCTSAVMIAGLALCAIAYHFLPADTTQNTNSGWQYVVLASIIIFLASYASG 449

  Fly   384 FGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLF 448
            .|.||| ...|:.|.::|...|...||.||....:::.:|..:..::...|.|.||...|.|||.
pombe   450 IGNIPW-QQAELFPMEVRALGAGFSTAINWVGNLIISASFLTMMESITPTGTFALFAGFCFVGLV 513

  Fly   449 FVIIFVPETRGKSLEEIER 467
            ......||..|.|:|.|.:
pombe   514 TSYFTYPELAGMSIENIHK 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	126/470 (27%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	119/455 (26%)
itr2	NP_593320.1	Sugar_tr	84..534	CDD:278511	127/473 (27%)
itr2	NP_593320.1	MFS	86..519	CDD:119392	120/456 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1095
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860