DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tret1-2 and ght5

DIOPT Version :9

Sequence 1:	NP_610694.1	Gene:	Tret1-2 / 36249	FlyBaseID:	FBgn0033644	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_587740.1	Gene:	ght5 / 2539240	PomBaseID:	SPCC1235.14	Length:	546	Species:	Schizosaccharomyces pombe

Alignment Length:	462	Identity:	108/462 - (23%)
Similarity:	214/462 - (46%)	Gaps:	56/462 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 MTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAV 120
            :||    |:..:......:.|::.:.:..|.....||::.:|:|::|:...:.:::..:|...||
pombe    47 VTD----SYSYSSARQGLITGMVNVGSFFGCFLSSPLMDRIGKRTSIMFWTIVYLIGIILQVTAV 107

  Fly   121 -NVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPT----ALGNIGILVCYVAGSF 180
             :.:.|:..:..||..:|..|:..|.:..|....::|||  ::.|    ..|.|.|..|...|:.
pombe   108 PSWVQIMVAKIWTGLSIGALSVLAPGFQSEVAPADLRGT--IVTTYQLAVTGGIFIAACINMGTH 170

  Fly   181 ---------------MNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGK 230
                           :.|.::.|:|    :.||      ||:||:.::.|::|.|.:.:  .:..
pombe   171 KLHKTAQWRVSMGINLLWGIITFIG----ISFL------PESPRYLISVGRDEEALQIM--AKNN 223

  Fly   231 EADVEPELKE----LMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYT 291
            :..:|.|:.:    :::|..:|:......|..|:|..:......:.||:|..||.:|.|...:|.
pombe   224 DLPIEHEVIQTEYHVIKSDCEAELAGGPATWPEIFGPDIRYRTFLGLGVMSLQQLTGDNYYFYYG 288

  Fly   292 VQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSI---LGGFF 353
            .::|:..|.. ...||.:|:..|||..||.|:.:::..||::.|.:..:...:|..|   :|...
pombe   289 FEVFEGTGMN-SPYLSALILDAVNFGCTFGGLFVLEFFGRRMPLIIGALWQSITFFIYAAVGNRA 352

  Fly   354 YCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFV 418
            ..:.:|......|.:.:....::|..|:..:||..::::||..|.:.|...|:|.|..||...|:
pombe   353 LTRKNGTSNHRAGAVMIVFSCLFIFSFAQTWGPAAYVIVGESYPIRYRSKCAAVATTGNWLWGFL 417

  Fly   419 VTKTFQDLTVAMG-AHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEI-ERKMMGRVPMSSVVNI 481
            ::.....:|.::| .:|  ::|.|..:.....:.:|..||:|.:|||| |..:.|..|.
pombe   418 ISFFTPFITNSIGFKYG--YIFAACNLCAACIIFLFAHETKGLTLEEINELYISGAKPW------ 474

  Fly   482 KPFPFNM 488
            .|.|.|:
pombe   475 MPRPKNL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tret1-2	NP_610694.1	Sugar_tr	31..467	CDD:278511	102/439 (23%)
Tret1-2	NP_610694.1	MFS	33..454	CDD:119392	94/425 (22%)
ght5	NP_587740.1	MFS	10..451	CDD:119392	94/424 (22%)
ght5	NP_587740.1	Sugar_tr	11..467	CDD:278511	103/440 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.800